The future of seizure detection
2018; Elsevier BV; Volume: 17; Issue: 3 Linguagem: Inglês
10.1016/s1474-4422(18)30034-6
ISSN1474-4465
Autores Tópico(s)Neonatal and fetal brain pathology
ResumoIn clinical practice, we rely on seizure diaries of our patients to manage epilepsy. In their Personal View 1 Elger CE Hoppe C Diagnostic challenges in epilepsy: seizure under-reporting and seizure detection. Lancet Neurol. 2018; (published online Jan 30.)http://dx.doi.org/S1474-4422(18)30038-3 Summary Full Text Full Text PDF PubMed Scopus (156) Google Scholar in The Lancet Neurology, Christian Elger and Christian Hoppe review the literature on the accuracy with which patients with epilepsy document their seizures. Elger and Hoppe conclude that under-reporting of seizures is an important clinical problem; less than half of the patients could accurately document their seizures, and more than half of all seizures captured during long-term video-electroencephalography (EEG) monitoring were unreported. Seizure under-reporting has implications in the management of individual patients, such as in adjustment of anti-epileptic drugs and in granting permission to drive a car. Accurate seizure documentation is also important because seizure under-reporting decreases the statistical power of associated clinical trials. Diagnostic challenges in epilepsy: seizure under-reporting and seizure detectionEpileptic seizures vary greatly in clinical phenomenology and can markedly affect the patient's quality of life. As therapeutic interventions focus on reduction or elimination of seizures, the accurate documentation of seizure occurrence is essential. However, patient self-evaluation compared with objective evaluation by video-electroencephalography (EEG) monitoring or long-term ambulatory EEG revealed that patients document fewer than 50% of their seizures, on average, and that documentation accuracy varies significantly over time. Full-Text PDF
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