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Effect-based and chemical analytical methods to monitor estrogens under the European Water Framework Directive

2018; Elsevier BV; Volume: 102; Linguagem: Inglês

10.1016/j.trac.2018.02.008

1879-3142

Sarah Könemann, Robert Kaše, Eszter Simon, Kees Swart, Sebastian Buchinger, Michael P. Schlüsener, Henner Hollert, Beate I. Escher, Inge Werner, Sélim Aït‐Aïssa, Etiënne L.M. Vermeirssen, Valeria Dulio, Sara Valsecchi, Stefano Polesello, Peter Behnisch, Barbora Javůrková, Olivier Perceval, Carolina Di Paolo, Daniel Olbrich, Eliška Sychrová, Rita Schlichting, Lomig Leborgne, Manfred Clara, Christoph Scheffknecht, Yves Marneffe, Carole Chalon, Petr Tušil, Přemysl Soldán, Brigitte von Danwitz, Julia Schwaiger, M. Isabel San-Martín, Francesca Bersani, Klára Hilscherová, Georg Reifferscheid, Thomas A. Ternes, Mario Carere,

Toxic Organic Pollutants Impact

The European Decision EU 2015/495 included three steroidal estrogens, estrone, 17β-estradiol and 17α-ethinyl estradiol, in the “watch-list” of the Water Framework Directive (WFD). As consequence, these substances have to be chemically monitored at the level of their environmental quality standards, which can be challenging. This project aimed to identify reliable effect-based methods (EBMs) for screening of endocrine disrupting compounds, to harmonise monitoring and data interpretation methods, and to contribute to the current WFD review process. Water and wastewater samples were collected across Europe and analysed using chemical analyses and EBMs. The results showed that 17β-estradiol equivalents were comparable among methods, while results can vary between methods based on the relative potencies for individual substances. Further, derived 17β-estradiol equivalents were highly correlated with LC-MS/MS analyses. This study shows that the inclusion of effect-based screening methods into monitoring programmes for estrogens in surface waterbodies would be a valuable complement to chemical analysis.