87 th Annual Meeting of the American Thyroid Association
2017; Mary Ann Liebert, Inc.; Volume: 27; Issue: S1 Linguagem: Inglês
10.1089/thy.2017.29046.abstracts
ISSN1557-9077
AutoresKevin T. Brumund, Stephanie J. Lee, Douglas Forrest, Yun‐Bo Shi, Linus Tsai, Hong Liu, Changyu Liu, Veerle Darras, John C. Morris, Victor Bernet, Angela M. Leung, Antônio C. Bianco, Carmelo Nucera, Gregory A. Brent, Julie Ann Sosa, R. Michael Tuttle, Honey V. Reddi, D. James Cooper, Michael W. Yeh, George J. Kahaly, J. Woody Sistrunk, Tanja Diana, Mingzhao Xing, Weiping Xing, Andrew G. Gianoukakis, Alex Tessnow, James D. Brierley, Virginia A. LiVolsi, Lori Worth, Kenneth W. Witwer, Jeffrey A. Knauf, Christina Schug, Mary H. Samuels, Ana L. Creo, Gerard M. Doherty, Maisie L. Shindo, Ralph P. Tufano, William B. Inabnet, Gregory W. Randolph, Naifa L. Busaidy, Amy Chen, Matthew D. Ringel, Andrew J. Bauer, John C. Cambier, Josef Koehrle, Kevin J. Phillips, Rengyun Liu, Yuri E. Nikiforov, Marius N. Stan, Meredith Hartley, Matt Lechner, Chirag M. Vyas, Ole‐Petter R. Hamnvik, Erik K. Alexander, P R Larsen, Trevor E. Angell,
Tópico(s)Thyroid Cancer Diagnosis and Treatment
ResumoThyroidVol. 27, No. S1 AbstractsFree Access87th Annual Meeting of the American Thyroid AssociationPublished Online:1 Oct 2017https://doi.org/10.1089/thy.2017.29046.abstractsAboutSectionsPDF/EPUB Permissions & CitationsPermissionsDownload CitationsTrack CitationsAdd to favorites Back To Publication ShareShare onFacebookTwitterLinked InRedditEmail 87th ANNUAL MEETING OF THE AMERICAN THYROID ASSOCIATION WEDNESDAY, OCTOBER 18, 20176:30 AM – 8:30 PMVCC, RegistrationATA Registration Open 6:30 AM – 6:30 PMVCC, West CoastATA Speaker Ready Room Open (Open to meeting faculty only) 7:00 AM – 3:00 PMVCC, SaanichATA Endocrine Neck Ultrasound Course(Satellite Program, separate registration required, additional fees apply, ECNU credits available)Co-Chairs: Kevin T. Brumund and Stephanie L. Lee 8:00 AM – 4:00 PMFairmont, Crystal BallroomE. Chester Ridgway (Ridgway) Trainee Conference: Clinical Trainees Symposium (Pre-registration required) 8:00 AM – 6:00 PMVCC, Crystal GardenATA Exhibit and Poster Hall Open (Open for exhibitor setup only) 7:30 AM – 1:30 PMFairmont, LibraryATA Board of Directors' Meeting (By invitation only) 1:00 PM – 4:00 PMVCC, Lecture TheatreRidgway Trainee Conference: Basic Trainees Symposium – Single Cell and Genomic Technologies (Open to all attendees; Pre-registration required)Douglas ForrestYun-Bo ShiLinus TsaiHong LiuChangyu LiuVeerle M. Darras2:00 PM – 2:30 PMVCC, LangfordInternational Coordinating Committee Meeting (by invitation only) 2:00 PM – 5:00 PMVCC, Metchosin16th International Thyroid Congress Program Organizing Committee Meeting (by invitation only) 2:45 PM – 4:00 PMVCC, Salon CATA Committee and Task Force Meetings(Open to current serving committee or task force members only) 5:30 PM – 5:45 PMVCC, Salon ABWelcome to the 87th Annual Meeting of the American Thyroid AssociationJohn C. Morris, ATA PresidentVictor J. Bernet, ATA Secretary/COOAngela M. Leung, Program Committee Co-ChairMingzhao Xing, Program Committee Co-Chair5:45 PM – 7:30 PMVCC, Salon ABOpening Session: Year in Thyroidology ReviewChair: Antonio C. Bianco Year in Basic ThyroidologyCarmelo Nucera Year in Clinical ThyroidologyGregory A. Brent Year in Surgical ThyroidologyJulie Ann Sosa7:30 PM – 9:00 PMVCC, Crystal GardenATA Welcome Reception in the Exhibit Hall(Meeting registration/badge required for entry; hall open to exhibitors and attendees) 87th ANNUAL MEETING OF THE AMERICAN THYROID ASSOCIATION THURSDAY, OCTOBER 19, 20176:00 AM – 7:45 AMVCC, Lecture TheatreEarly Riser Satellite Program: Diagnosis and Management of Advanced Thyroid Cancer (Limited seating; first-come, first served; light breakfast offered)R. Michael Tuttle6:45 AM – 5:15 PMVCC, RegistrationATA Registration Open 7:00 AM – 5:30 PMVCC, West CoastATA Speaker Ready Room Open (Open to meeting faculty only) 7:00 AM – 8:00 AMVCC, Salon CATA Women in Thyroidology: Women and the Future of Endocrinology (Pre-registration required; ticket required for entry)Chair: Honey V. ReddiDavid S. CooperStephanie L. Lee8:00 AM – 8:05 AMVCC, Salon ABWelcome to the 87th Annual Meeting of the American Thyroid AssociationJohn C. Morris, ATA PresidentVictor J. Bernet, ATA Secretary/COOAngela M. Leung, Program Committee Co-ChairMingzhao Xing, Program Committee Co-Chair8:05 AM – 8:50 AMVCC, Salon ABATA Van Meter Lecture (announced onsite at time of lecture) 8:50 AM – 9:50 AMVCC, Salon ABHighlighted Oral Abstracts Session (4 total abstracts)Co-Chairs: Angela M. Leung and Mingzhao Xing Oral Abstract #1: Incident Hypothyroidism During Tyrosine Kinase Inhibitor Therapy Predicts Significantly Longer Survival in Patients with Advanced Non-Thyroid CancersTrevor E. Angell Oral Abstract #2: Sumoylation of TRβ Plays an Essential Role in Regulation of the Hypothalamic-Pituitary-Thyroid (HPT) AxisSujie Ke Oral Abstract #3: TERT Mutations Increase Risk of Treatment Failure in BRAF Positive Papillary Thyroid CancerDaria Handkiewicz-Junak Oral Abstract #4: Combined Mycophenolate With Intravenous Methylprednisolone Therapy Is More Effective Than Intravenous Methylprednisolone Alone in Active and Moderate-to-Severe Graves' Orbitopathy – A Randomized, Observer Blind, Multicenter TrialGeorge J. Kahaly8:50 AM – 11:45 AMFairmont, Crystal BallroomRidgway Trainee Conference: Surgical Considerations in Management of the Thyroid (Open to all attendees; Pre-registration required)Moderator: Elizabeth G. Grubbs 9:30 AM – 4:30 PMVCC, Crystal GardenExhibit and Poster Hall Open(Open at 8:00 AM to poster presenters and exhibitors only) 9:50 AM – 10:45 AMVCC, Crystal GardenPoster Review Session and Break in the Exhibit HallPosters 35–173; Short Call Posters 9–25 10:45 AM – 12:00 PMVCC, Lecture TheatreBasic Symposium: Thyroid Hormone TransportersChair: Peter A. Kopp Thyroid Hormone Transport in The BrainJuan Bernal Triac for the Treatment of MCT8 DeficiencyW. Edward Visser Virus 9-Based Gene Therapy Delivery of MCT8 in the BrainSamuel Refetoff10:45 AM – 12:00 PMVCC, Salon ABClinical Symposium: New Directions in Thyroid Nodules and Thyroid CancerChair: Bryan R. Haugen An Update: The NEW Bethesda Classification System for Reporting Thyroid CytopathologyJeffrey F. Krane AJCC 8th Edition Update on Differentiated Thyroid CancerR. Michael Tuttle AJCC 8th Edition with Focus on Patient Age: Is There Actually an Age Cutoff?Sanziana A. Roman Moving Towards Perfection: Avoiding Unnecessary Surgery,Eliminating Complications, and Reducing CostsMichael W. Yeh12:00 PM – 1:00 PMVCC, Crystal GardenExhibit Hall Closed (Lunch on your own) 12:00 PM – 1:00 PMVCC, SaanichRidgway Trainees Conference: University of Southern California Thyroid Research Group Fellows Fund Basic Trainees Lunch Session – Selling Your Science (Open to all trainees; Lunch ticket required for meal)Moderator: David S. SharlinHoney V. ReddiDavid S. Sharlin12:00 PM – 1:00 PMFairmont, Crystal BallroomRidgway Trainees Conference: Arthur Bauman Clinical Trainees Lunch Session – Setting Up a Thyroid Practice (Open to all trainees; Lunch ticket required for meal)J. Woody SistrunkKatarzyna Piotrowska12:00 PM – 1:00 PMVCC, Oak BayATA Expo Theatre Presented by CBLPath/UPMC: Molecular Markers – The New Era(Limited seating; first-come, first served; lunch offered)Steven P. HodakYuri NikiforovBryan R. Haugen1:00 PM – 1:45 PMVCC, Salon ABLewis E. Braverman Distinguished Award LectureshipRe-Telling the Story About Thyroid Cancer – Rising Incidence, Mortality and Maybe an ExplanationIntroduction by Tracy S. WangJulie Ann Sosa1:45 PM – 3:15 PMFairmont, Crystal BallroomRidgway Trainee Conference: Trainees Thyroid Ultrasound Course (Open to all trainees)Introduction to Thyroid UltrasoundSonographic Assessment of Thyroid NodulesNeck Ultrasound: Beyond NodulesTracey S. TyleeSteven P. WeitzmanAlex Tessnow1:50 PM – 3:05 PMVCC, Lecture TheatreBasic/Translational Oral Abstracts Session: Autoimmune Thyroid Diseases (5 total)Co-Chairs: Chao Liu and Laura Fugazzola Oral Abstract #5: Interferon Alpha Triggers Autoimmune Thyroiditis via Degradation of Thyroglobulin by Cysteine Cathepsins into Immunogenic PeptidesLarissa C. Faustino Oral Abstract #6: First Report of Tree Shrew Graves' Disease ModelLiping Wu Oral Abstract #7: Identification of Novel Sodium Iodide Symporter (NIS) Interactors which Modulate Iodide UptakeAlice Fletcher Oral Abstract #8: Performance and Specificity of Six Immunoassays for TSH Receptor Antibodies - A Multicenter StudyTanja Diana Oral Abstract #9: Functional AIM2 Inflammasome Expressed inThyrocytes Are Associated with Autoimmune ThyroiditisQingling Guo1:50 PM – 3:05 PMVCC, Salon ABClinical Oral Abstracts Session: Iodine Status and Thyroid Function in Pregnancy (5 total)Co-Chairs: Sun Y. Lee and Jorge H. Mestman Oral Abstract #10: Development and Validation of a Novel Iodine-129 Tracer Method for the Safe Assessment of Iodine Absorption and Thyroidal Uptake from Oral Iodine Supplements and Foods in HumansMichael B. Zimmermann Oral Abstract #11: Incidence of Neonatal Hyperthyroidism Among Newborns of Graves' Disease Patients Treated With Radioiodine Therapy Within Two Years Before ConceptionAi Yoshihara Oral Abstract #12: Different FT4 Response to HCG Under TPOAb or TgAb During First- Half TrimesterYuanyuan Hou Oral Abstract #13: Different Trajectories of Thyroid Function During Pregnancy: A New Approach to Look at Physiological Changes of Thyroid Function During GestationVictor Pop Oral Abstract #14: The Association of Phthalate Exposure With Thyroid Function During Pregnancy: A Mixture AnalysisTim Korevaar3:05 PM – 4:00 PMVCC, Crystal GardenPoster Review Session and Break in the Exhibit Hall 3:05 PM – 4:00 PMVCC, Oak BayATA Expo Theatre Presented by Veracyte, Inc.: Leveraging Enriched Genomic Data to Develop a Next-Generation Afirma Gene Expression Classifier (Limited seating; first-come, first served)Richard T. KloosGiulia C. Kennedy3:15 PM – 4:30 PMFairmont, Crystal BallroomRidgway Trainee Conference: Case Discussions – Thyroid Nodules (Open to all trainees)Moderators: Mara Y. Roth and Steven P. WeitzmanStephanie L. LeeGregory W. RandolphJennifer A. Sipos4:00 PM – 4:45 PMVCC, Salon ABATA Research Grants SessionChair: Motoyasu Saji Exploring Genetics of Advanced Thyroid CancerMing Li Cancer Progression and Therapeutic Response in a Mouse Model of Medullary Thyroid CarcinomaSarah C. Oltmann The Role of the Renal Na+/I- Symporter (NIS) in Iodide Metabolism and Thyroid FunctionMarcela Andrea Reyna-Neyra4:50 PM – 5:45 PMDiscussion-Debates/ Meet the Professor Workshops (6 total) VCC, Salon C• DM 1: Mechanisms in Immune Pathogenesis of Thyroid DiseasesModerator: Matthew D. RingelIDO1 and RET/PTC in Immune Dysregulation in Thyroid CancerGenetic-Epigenetic Dysregulation in Autoimmune Thyroid DiseasesEfisio PuxedduYaron TomerVCC, Colwood• DM 2: DeiodinasesModerator: Anthony N. HollenbergType 3 Deiodinase in the Regulation of the Leptin-Melanocortin System and Circadian ActivityPathophysiological Relevance of Deiodinases PolymorphismsArturo HernandezAntonio C. BiancoVCC, Salon AB• DM 3: Effects of Drugs and Medications on TFTs Moderator: Leonard Wartofsky Medication Effects Biotin EffectsDavid H. SarneAlicia Algeciras-SchimnichVCC, Sidney• DM 4: Ethics in Thyroid Research Moderator: M. Sara Rosenthal Ethical dilemmas in Clinical Thyroid Research Ethical dilemmas in Basic Thyroid ResearchPeter AngelosRebecca E. SchweppeVCC, Esquimalt• DM 5: Consequences of Environmental Thyroid Disruptors: Knowns and UnknownsModerator: Angela M. LeungThe Burden of Low-Level Environmental Thyroid Toxicants: Potential Impacts on Health Exposure to Thyroid Disruptors in Pregnancy and InfancyTim KorevaarRobin P. PeetersVCC, Saanich• DM 6: Intraoperative Consultation of Thyroid Nodules: An Interactive Approach Between a Surgeon and a PathologistModerator: Robert C. SmallridgeThe Surgeon's PerspectiveThe Pathologist's PerspectiveJohn D. CaslerQihui Jim Zhai6:00 PM – 7:15 PMVCC, Lecture TheatreATA Annual Business Meeting(for Active and Senior ATA members only)The annual business meeting features election results, committee reports, discussion and voting on important member issues. 87th ANNUAL MEETING OF THE ATA FRIDAY, OCTOBER 20, 20176:00 AM – 7:45 AMVCC, Lecture TheatreEarly Riser Satellite Symposium Presented by Quidel Corporation:TSH Receptor Antibodies – Methodology and Clinical Relevance (Limited seating; first-come, first served; light breakfast offered)George J. KahalyJ. Woody SistrunkTanja Diana7:30 AM – 5:15 PMVCC, RegistrationATA Registration Open 7:30 AM – 5:30 PMVCC, West CoastATA Speaker Ready Room Open (Open to meeting faculty only) 8:00 AM – 8:05 AMVCC, Salon ABMorning AnnouncementsAngela M. LeungMingzhao Xing8:05 AM – 8:50 AMVCC, Salon ABPlenary Lecture: Iodine Intake and Thyroid Diseases – Learnings in ChinaIntroduction by Mingzhao XingWeiping Teng8:45 AM – 10:30 AMFairmont, Crystal BallroomRidgway Trainee Conference: Case Discussions – Thyroid Cancer(Open to all trainees)Moderators: Andrew G. Gianoukakis and Alex TessnowJames D. BrierleyVirginia A. LiVolsiR. Michael TuttleLori J. Worth8:50 AM – 9:50 AMVCC, Lecture TheatreBasic/Translational Oral Abstracts Session: Thyroid Cancer (4 total)Co-Chairs: Jason D. Prescott and Yufei Shi Oral Abstract #15: Berberine Could Inhibit Thyroid Carcinoma Cells by Inducing Mitochondrial Apoptosis, G0/G1 Cell Cycle Arrest and Suppressing Migration Via PI3K-AKT and MAPK Signaling PathwaysLiang Li Oral Abstract #16: Large Oncosomes of Anaplastic and Papillary Thyroid Cancer CellsKenneth W. Witwer Oral Abstract #17: Co-Evolution of Met Amplification and Hgf Overexpression Mediate Resistance to BRAFV600E Inactivation in Murine Anaplastic Thyroid Cancers and Sensitizes Them to MET Kinase InhibitorsJeffrey A. Knauf Oral Abstract #18: TGFβ1-Induced Radioiodine Therapy of Hepatocellular Cancer After Mesenchymal Stem Cell (MSC)-Mediated Sodium Iodide Symporter (NIS) Gene DeliveryChristina Schug8:50 AM – 9:50 AMVCC, Salon ABClinical Oral Abstracts Session: Thyroid Dysfunction and Pediatric Thyroid Disease (4 total)Co-Chairs: Yaron Tomer and Catherine A. Dinauer Oral Abstract #19: Graves' Disease and Its Effect on Medial Temporal Lobe StructuresMats Holmberg Oral Abstract #20: Higher Remission Rate After Long-Term Methimazole Therapy in Patients with Graves' Disease: A Randomized Clinical TrialFereidoun Azizi Oral Abstract #21: Effects of Altering Levothyroxine (L-T4) Doses on Quality of Life, Mood and Cognition in L-T4 Treated Subjects: A Double-Blinded, Randomized, Controlled TrialMary H. Samuels Oral Abstract #22: Accuracy of Adult ATA Ultrasound Risk Stratification in ChildrenAna L. Creo9:30 AM – 4:30 PMVCC, Crystal GardenExhibit and Poster Hall Open(Open at 8:00 AM to poster presenters and exhibitors only) 9:50 AM – 10:45 AMVCC, Crystal GardenPoster Review Session and Break in the Exhibit HallPosters 174–311; Short Call Posters 26–43 9:50 AM – 10:35 AMVCC, Lecture TheatreHighlights of ATA VideoEndocrinologyModerator: Gerard M. Doherty Lateral Neck Dissection for Thyroid CancerMaisie L. Shindo Central Neck Dissection for Thyroid CancerRalph P. Tufano Remote Access Thyroid SurgeryWilliam Barry Inabnet10:45 AM – 12:00 PMVCC, Lecture TheatreBasic Symposium: Modulation of TSHR in Thyroid DiseaseModerator: Antonio Di Cristofano TSHR and IGF1-R CrosstalkMarvin C. Gershengorn TSHR Neutral AntibodiesSyed Morshed Central Tolerance to the TSHR and Graves' DiseaseRicardo Pujol-Borrell10:45 AM – 12:00 PMVCC, Salon ABClinical Symposium: Thyroid Dysfunction Grand Rounds – Case DiscussionsModerator: Mary SamuelsPanelists: Anne R. Cappola, Stephanie L. Lee, John C. Morris, Paul W. Ladenson and Douglas S. Ross 12:00 PM – 1:00 PMVCC, Crystal GardenExhibit Hall Closed (Lunch on your own) 12:00 PM – 1:00 PMFairmont, Crystal BallroomRidgway Trainee Conference: All Trainees Lunch Session – How to Get Your Work Published (Open to all trainees; Lunch ticket required for meal)Peter A. Kopp12:00 PM – 1:00 PMVCC, Oak BayATA Expo Theatre Presented by Sanofi Genzyme: Employing Thyroglobulin Assay for Risk Stratification in the Management of Differentiated Thyroid Cancer(Limited seating; first-come, first served; lunch offered)Leonard Wartofsky1:00 PM – 1:45 PMVCC, Salon ABPaul Starr Award LectureTechnical and Technological Advances that Changed Thyroid SurgeryIntroduction by Gerard M. DohertyQuan-Yang Duh1:50 PM – 3:05 PMVCC, Lecture TheatreBasic Symposium: MicroRNAs in Thyroid CancerModerator: Electron Kebebew Integrated Genomic Analysis in Thyroid FNAThomas Giordano MicroRNA in Thyroid Follicular Cell Differentiation and CarcinogenesisPilar Santisteban MicroRNA-LOX-SLUG Axis in Thyroid Cancer ProgressionMyriem Boufraqech1:50 PM – 3:05 PMVCC, Salon ABClinical Symposium: Thyroid and PregnancyChair: John H. Lazarus Subclinical Hypothyroidism in Pregnancy: Implications and ControversiesSpyridoula Maraka Is Pregnancy a Risk Factor for Thyroid Cancer Progression?Luba Rakhlin 2017 ATA Thyroid in Pregnancy GuidelinesElizabeth N. Pearce1:50 PM – 3:20 PMFairmont, Crystal BallroomRidgway Trainee Conference: Case Discussions – Thyroid Function (Open to all trainees)Moderators: Tracey S. Tylee and Jennifer A. MorrisonCatherine A. DinauerPeter A. SingerLeonard Wartofsky3:05 PM – 4:00 PMVCC, Crystal GardenPoster Review Session and Break in the Exhibit Hall 3:05 PM – 4:00 PMVCC, Oak BayATA Expo Theatre Presented by Interpace Diagnostics: Advances in Molecular Testing of Indeterminate Thyroid Nodules – ThyGenX® and ThyraMIR®(Limited seating; first-come, first served)Thomas J. FaheyDavid Lieu4:00 PM – 4:15 PMVCC, Salon ABPresentation of ATA AwardsPresented by John C. Morris, ATA President2017 ATA Distinguished Service Award2017 John B. Stanbury Thyroid Pathophysiology MedalBryan R. HaugenJames A. Fagin4:15 PM – 5:00 PMVCC, Salon ABClark T. Sawin Historical Vignette1967–2017: From Resistance to Thyroid Hormone to Thyroid Hormone ReceptorsModerator: Peter Kopp; Introduction by Donald St. GermainSamuel RefetoffGilbert H. DanielsDouglas ForrestCarla Moran5:05 PM – 6:00 PMDiscussion-Debates/ Meet the Professor Workshops (6 total) VCC, Salon AB• DM 7: Radioiodine-Refractory Thyroid Cancer Moderator: Naifa Lamki Busaidy Genetic Backgrounds and Mechanisms of Radioioidine-Refractory Thyroid CancerTargeting Signaling Pathways to Restore Radioiodine Avidity of Thyroid CancerYan-Song LinSissy M. JhiangVCC, Sidney• DM 8: Stem Cells in Thyroidology Moderator: Sheue-yann Cheng Differentiation of Human Embryonic Stem Cells into Thyrocytes Thyroid Hormone Regulates Intestine Stem Cell Development during Xenopus Laevis MetamorphosisTerry F. DaviesYun-Bo ShiVCC, Esquimalt• DM 9: Autoimmune Thyroiditis Moderator: Salvatore Benvenga The Role of Iodine The Role of SeleniumLeonidas DuntasJosef KoehrleVCC, Colwood• DM 10: Epidemiology of Thyroid Function and Common DiseasesModerator: David S. CooperThyroid Function and Cardiovascular Disease: Underlying Mechanisms Hypothyroidism in Chronic Kidney Disease: Physiologic Adaptation or Physiologic Entity?Layal ChakerConnie M. RheeVCC, Saanich• DM 11: Pediatric Thyroid Cancer Moderator: Steven G. Waguespack Recent Progress in Genetics of Pediatric Thyroid Cancer The Role of FNAB in Pediatric Thyroid NodulesAli S. AlzahraniAndrew J. BauerVCC, Lecture Theatre• DM 12: Thyroid Cancer Management – Novel Therapeutics and Management Options(Workshop co-sponsored by SNMMI)Moderator: James V. HennesseyTreatment of Distant Metastatic Follicular Thyroid Cancer: Radioactive Iodine Therapy and BeyondEvaluation and Management of Patients with Differentiated Thyroid Cancer (DTC), Positive Thyroglobulin Levels (+Tg), and Negative Diagnostic Radioiodine Scans (-DxSc)Mona M. SabraDouglas Van Nostrand7:30 PM – 11:00 PMRoyal BC Museum675 Belleville StreetATA Annual Banquet at the Royal BC Museum(Ticketed event, pre-registration required; comfortable shoes encouraged)The Royal BC Museum is located across the street from the Fairmont and VCC. Tour the First Nations and Modern History museum galleries, enjoy great food along the way at various food stations and socialize with colleagues and friends. 87th ANNUAL MEETING OF THE ATA SATURDAY, OCTOBER 21, 20176:00 AM – 7:45 AMVCC, Lecture TheatreEarly Riser Satellite Symposium Presented by AACE: Current Landscape in Medullary Thyroid Cancer – Update for Clinicians(Limited seating; first-come, first served; light breakfast offered)Gregory W. RandolphNaifa Lamki BusaidyAmy Y. ChenMatthew D. Ringel7:30 AM – 5:15 PMVCC, RegistrationATA Registration Open 7:30 AM – 5:30 PMVCC, West CoastATA Speaker Ready Room Open (Open to meeting faculty only) 8:00 AM – 8:05 AMVCC, Salon ABMorning AnnouncementsAngela M. LeungMingzhao Xing8:00 AM – 12:15 PMVCC, Salon CATA Pediatric Thyroid Forum Satellite Program: Update on Pediatric Thyroid Disease 2017 – Current State and Future DirectionsChair: Andrew J. Bauer 8:05 AM – 8:50 AMVCC, Salon ABPlenary Lecture: Understanding How Breaches in Immune Tolerance Lead to Autoimmune Thyroid DiseaseIntroduction by Angela M. LeungJohn Cambier8:45 AM – 9:15 AMFairmont, Crystal BallroomRidgway Trainee Conference: Highlighted Trainee Abstracts Short Oral Presentations (Open to all trainees)Moderator: Tracey S. Tylee Basic - De Novo Tri-iodothyronine (T3) FormationCintia E. Citterio Clinical - Differential Growth Rates of Benign Versus Malignant Thyroid NodulesChirag M. Vyas Case Report - The First Report of a Homozygous HSA Gene Mutation Causing Familial Dysalbuminemic HyperthyroxinemiaMizuho Mimoto8:50 AM – 9:50 AMVCC, Lecture TheatreBasic/Translational Short Call Oral Abstracts Session (4 total)Chair: Mabel M. Ryder Short Call Oral Abstract #1: The Nuclear and Mitochondrial Genomes of Hürthle Cell Carcinoma and Its MetastasesRaj Gopal Short Call Oral Abstract #2: Modulation of Cholesterol and Sex Steroid Metabolism by 3,5-T2 in Lipid-Loaded Primary Mouse HepatocytesJosef Koehrle Short Call Oral Abstract #3: Challenging the Adipocyte Color Barrier - TR Activation Elicits a White to Beige Transdifferentiation Independent of Beta-Adrenergic SignalingKevin J. Phillips Short Call Oral Abstract #4: Radioiodine Refractoriness Is a Mechanism in the Increased Recurrence of Papillary Thyroid Cancer Driven by Coexisting BRAF V600E and TERT Promoter MutationsRengyun Liu8:50 AM – 9:50 AMVCC, Salon ABClinical Short Call Oral Abstracts Session (4 total)Chair: Gregory W. Randolph Short Call Oral Abstract #5: Clinical Validation of ThyroSeq v3® Performance in Thyroid Nodules with Indeterminate Cytology: A Prospective Blinded Multi-Institutional Validation StudyYuri Nikiforov Short Call Oral Abstract #6: Development and Validation of Classifiers to Enhance the Afirma Genomic Sequencing Classifier Performance Among Hürthle Cell SpecimensQuan-Yang Duh Short Call Oral Abstract #7: Emergence of V804M Resistance Gatekeeper Mutation in Sporadic Medullary Thyroid Carcinoma Patients Treated with TKI Tyrosine Kinase InhibitorsNaifa Lamki Busaidy Short Call Oral Abstract #8: A Multicenter, Randomized, Open-label, Phase 2 Trial of Donafenib in Progressive Local or Metastatic Radioiodine-Refractory Differentiated Thyroid Cancer: A Preliminary Short-Term Report of Efficacy and SafetyHui Li9:15 AM – 10:00 AMFairmont, Crystal BallroomRidgway Trainee Conference: How to Communicate About the Thyroid (Open to all trainees)Moderator: Andrew G. GianoukakisGerard M. DohertyVirginia A. LiVolsiAndrew G. Gianoukakis9:30 AM – 1:30 PMVCC, Crystal GardenExhibit and Poster Hall Open(Open at 8:00 AM to poster presenters and exhibitors only) 9:50 AM - 10:45 AMVCC, Crystal GardenPoster Review Session and Break in the Exhibit HallPosters 312–450; Short Call Posters 44–57 9:50 AM – 10:45 AMVCC, Crystal GardenTrainee Poster Contest in the Exhibit Hall(For ATA Trainee Poster Contest judges) 10:45 AM – 12:00 PMVCC, Lecture TheatreBasic Symposium: Novel Molecular Mechanisms of Thyroid CancerChair: Young Kee Shong Nuclear Receptor Signaling Abnormalities in Thyroid CancerFrances E. Carr Synergistic Oncogene Interactions in Thyroid Cancer Progression and Clinical OutcomesYoung Shin Song Novel Mutations in Benign Thyroid Neoplasms: Results from Whole Exome SequencingGuang Ning10:45 AM – 12:00 PMVCC, Salon ABClinical Symposium: Surgical Treatment of Thyroid Cancer – The Fine ArtsChair: Emad Kandil Subtleties in Surgical Management of Recurrent Differentiated Thyroid CancerRalph P. Tufano Intraoperative Neuromonitoring in Thyroidectomy for Thyroid CancerGaosong Wu Trans-Oral Robotic Thyroid Surgery for Papillary Thyroid CancerHoon Yub Kim12:00 PM – 1:00 PMVCC, Crystal GardenPoster Review and Break in the Exhibit Hall 12:00 PM – 1:00 PMVCC, SaanichRidgway Trainee Conference: Basic Trainees Lunch Session – Career Tracks (Open to all trainees; Lunch ticket required for meal)Moderator: Salma KhanAimee T. FrancoVeerle Darras12:00 PM – 1:00 PMFairmont, Crystal BallroomRidgway Trainee Conference: Clinical Trainees Lunch Session – Career Tracks (Open to all trainees; Lunch ticket required for meal)Moderator: Steven P. WeitzmanJay WatskyJoshua P. KlopperStephanie A. FishRichard T. Kloos12:00 PM – 1:00 PMVCC, Oak BayATA Expo Theatre Presented by Eisai, Inc.: LENVIVA Product Theatre (Limited seating; first-come, first served; lunch offered)Bryan McIver1:00 PM – 1:45 PMVCC, Salon ABSidney H. Ingbar Distinguished Award LectureshipGenomic Evolution of Thyroid Nodules and Cancer – New Answers to Old QuestionsIntroduction: Sally E. CartyYuri Nikiforov1:30 PMVCC, Crystal GardenExhibit and Poster Hall Closes 1:50 PM – 3:05 PMVCC, Lecture TheatreBasic Symposium: Novel Drug Treatments in Thyroid Oncology – An UpdateChair: Steven I. Sherman Novel Drug Treatments of Medullary Thyroid CancerRossella Elisei Novel Drug Treatments of Differentiated Thyroid CancerDouglas W. Ball Novel Drug Treatments of Anaplastic Thyroid CancerKeith C. Bible1:50 PM – 3:05 PMVCC, Salon ABArthur Bauman Clinical Symposium: Thyroid AutoimmunityChair: Terry F. Davies Thyroid Autoimmunity: Overlap with Other Autoimmune DiseasesGeorge J. Kahaly Thyroid Autoimmunity in the ElderlyKristien Boelaert Current Treatment Standards and Future Perspectives of Graves' DiseaseMarius Stan2:00 PM – 4:00 PMFairmont, ShaughnessyATA Alliance for Patient Education Free Public Forum(Open to the general public and all meeting attendees)Sponsored by the ATA Alliance members: American Thyroid Association, Bite Me Cancer, Graves' Disease and Thyroid Foundation, Light of Life Foundation, ThyCa: Thyroid Cancer Survivors' Association, Inc., Thyroid Cancer Canada and Thyroid Federation International 3:05 PM – 3:20 PMVCC, Salon AB FoyerRefreshment Break 3:20 PM – 4:50 PMVCC, Lecture TheatreBasic/Translational Oral Abstracts Session: Thyroid Hormone and Receptor (6 total)Co-Chairs: Vasyl V. Vasko and Linwah Yip Oral Abstract #23: Thyromimetics Lower Cerebral Levels of Very Long Chain Fatty Acids in Mouse Model of X-Linked AdrenoleukodystrophyMeredith D. Hartley Oral Abstract #24: MCT8–Dependent Thyroid Hormone Uptake Promotes Neurogenesis and Radial Cell Migration Crucial for Proper Cortical DevelopmentVeerle M. Darras Oral Abstract #25: Molecular and Genetic Analyses of the Function of Thyroid Hormone Receptor Coactivator SRC3 During Xenopus Postembryonic DevelopmentLingyu Bao Oral Abstract #26: Thyroid Hormone Regulates KiSS1 Gene Expression Through PI3K/Akt-mTOR Signaling Pathway and Specificity Protein-1Gang Chen Oral Abstract #27: Non-Genomic Effects of Thyroid Hormones on Mesenchymal Stem Cells and AngiogenesisKathrin A. Schmohl Oral Abstract #28: Probing the Thyroid Phenotype of Sbp2 DeficiencyHaruki Fujisawa3:20 PM – 4:50 PMVCC, Salon ABClinical Oral Abstracts Session: Thyroid Cancer (6 total)Chair: Masha Livhits and Douglas Van Nostrand Oral Abstract #29: Clinical Validation of the Afirma Genomic Sequencing Classifier for Medullary Thyroid CancerGregory W. Randolph Oral Abstract #30: Ultrasound-Guided Radiofrequency Ablation of Low- Risk Papillary Thyroid Microcarcinoma: A Prospective Study on 421 PatientsMingbo Zhang Oral Abstract #31: Thyroglobulin Does Not Correlate With Response in Radioactive Iodine Refractory (RAIR) BRAF Mutated Papillary Thyroid Cancer (PTC) Treated With Dabrafenib Alone or in Combination with TrametinibBhavana Konda Oral Abstract #32: Age and Gender Distribution of Thyroid Nodular Lesions Found in Thyroid Ultrasound Examination Within Three Years After the Nuclear Accident: The Fukushima Health Management SurveyHiroki Shimura Oral Abstract #33: US Prediction of Highly Aggressive TERT Promoter- Mutated Papillary Thyroid CancerTae Hyuk Kim Oral Abstract #34: Patient Age-Associated Mortality Risk Is Differentiated by the BRAF V600E Status in Papillary Thyroid CancerXiaopei Shen4:50 PM – 5:45 PMDiscussion-Debates/ Meet the Professor Workshops (6 total)VCC, Saanich• DM 13: Novel Genetic Mouse Models for Basic Thyroid Research Moderator: James A. Fagin Genetic Mouse Models on Thyroid Hormones in Hearing Transgenic Mouse Models in the Thyroid Cancer MicroenvironmentDouglas ForrestAime T. FrancoVCC, Salon AB• DM 14: Low-Risk Thyroid Cancer Moderator: Anna M. Sawka Cancers That Don't Require Surgery at All: Micro-PTC Observation Cancers that are not Cancers (NIFTP)Allen S. HoYuri NikiforovVCC, Salon C• DM 15: Updates in the Understanding of T3, T4, and Thyroid Hormone Derivatives Moderator: Brian W. Kim Combination T3 and T4: What's New? Thyronamines – Thyroid Hormone Derivatives: Biological Actions and Clinical ImplicationsJacqueline JonklaasRiccardo ZucchiVCC, Esquimalt• DM 16: Obesity and the Thyroid Moderator: Lewis E. Braverman Thyroid Function in Weight Gain: Underlying Mechanisms Thyroid Function and the Metabolic SyndromeShen QuSun Y. LeeVCC, Colwood• DM 17: Quality of Life in Thyroid Disease Moderator: Jeffrey R. Garber The ThyPRO Quality of Life Questionnaire Quality of Life in Thyroid Cancer PatientsTorquil WattBrisa Aschebrook-Kilfoy and Raymon H. GroganVCC, Lecture Theatre• DM 18: Use of PET Imaging in Thyroid Nodules and Thyroid Cancer Moderator: Kenneth D. Burman Evaluation of Incidental PET-Positive Thyroid Lesions Use of PET Imaging in Thyroid Cancer: Indications and InterpretationJacques HowMehrbod Javadi87th ANNUAL MEETING OF THE ATA SUNDAY, OCTOBER 22, 20177:45 AM – 11:15 AMFairmont, Palm CourtATA Registration Open 8:00 AM – 8:05 AMFairmont, Crystal BallroomMorning/Closing AnnouncementsAngela M. LeungMingzhao Xing8:05 AM – 9:20 AMFairmont, Crystal BallroomIodine Global Network SymposiumChair: Elizabeth N. Pearce Understanding Iodine Sources in National DietsJonathan Gorstein Status and Source of Iodine in U.S. DietsCria G. Perrine The Current Status of Iodine Nutrition in CanadaMary L'Abbe9:25 AM – 11:00 AMFairmont, Crystal BallroomThyroid Cancer Tumor BoardModerator: Manisha H. Shah Endocrinology/Molecular MarkersBryan McIver OncologyLori J. Wirth SurgeryGregory W. Randolph SurgeryDavid J. Terris Pathology/Molecular MarkersRonald A. Ghossein Thyroid SonographyJennifer A. Sipos RadiologyJames D. Brierley11:00
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