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BIBTEX RIS

Mumiamicin: Structure and bioactivity of a new furan fatty acid from <i>Mumia</i> sp. YSP-2-79

2018; Microbiology Research Foundation; Volume: 64; Issue: 2 Linguagem: Inglês

10.2323/jgam.2017.06.004

ISSN

1349-8037

Autores

Tōru Kimura, Ayano Tajima, Yuki Inahashi, Masato Iwatsuki, Hiroaki Kasai, Takayuki Mokudai, Yoshimi Niwano, Kazuro Shiomi, Yōko Takahashi, Satoshi Ōmura, Takuji Nakashima,

Tópico(s)

Genomics and Phylogenetic Studies

Resumo

A new antibiotic, designated mumiamicin, was isolated from the cultured broth of the rare actinomycete strain, Mumia sp. YSP-2-79, by Diaion HP-20, silica gel and ODS column chromatography, followed by HPLC purification. The chemical structure of mumiamicin was elucidated as a new furan fatty acid by nuclear magnetic resonance and mass spectrometry. Mumiamicin showed antimicrobial activity and antioxidative activity.

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