The Effect of Plastic Deformation on the Cell Viability and Adhesion Behavior in Metallic Implant Materials
2018; Wiley; Linguagem: Inglês
10.1002/9781119423829.ch16
ISSN2637-4390
Autores Tópico(s)Additive Manufacturing and 3D Printing Technologies
ResumoChapter 16 The Effect of Plastic Deformation on the Cell Viability and Adhesion Behavior in Metallic Implant Materials B. Uzer, B. Uzer buzer@ku.edu.tr Koç University, Advanced Materials Group (AMG), Department of Mechanical Engineering, Sariyer, İstanbul, TurkeySearch for more papers by this authorD. Canadinc, D. Canadinc Koç University, Advanced Materials Group (AMG), Department of Mechanical Engineering, Sariyer, İstanbul, Turkey Koç University Surface Science and Technology Center (KUYTAM), Sariyer, İstanbul, TurkeySearch for more papers by this author B. Uzer, B. Uzer buzer@ku.edu.tr Koç University, Advanced Materials Group (AMG), Department of Mechanical Engineering, Sariyer, İstanbul, TurkeySearch for more papers by this authorD. Canadinc, D. Canadinc Koç University, Advanced Materials Group (AMG), Department of Mechanical Engineering, Sariyer, İstanbul, Turkey Koç University Surface Science and Technology Center (KUYTAM), Sariyer, İstanbul, TurkeySearch for more papers by this author Book Editor(s):Narottam P. Bansal, Narottam P. BansalSearch for more papers by this authorRicardo H.R. Castro, Ricardo H.R. CastroSearch for more papers by this authorMichael Jenkins, Michael JenkinsSearch for more papers by this authorAmit Bandyopadhyay, Amit BandyopadhyaySearch for more papers by this authorSusmita Bose, Susmita BoseSearch for more papers by this authorAmar Bhalla, Amar BhallaSearch for more papers by this authorJ. P. Singh, J. P. SinghSearch for more papers by this authorMorsi M. Mahmoud, Morsi M. MahmoudSearch for more papers by this authorGary Pickrell, Gary PickrellSearch for more papers by this authorSylvia Johnson, Sylvia JohnsonSearch for more papers by this author First published: 12 February 2018 https://doi.org/10.1002/9781119423829.ch16Citations: 3Book Series:Ceramic Transactions Series AboutPDFPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShareShare a linkShare onFacebookTwitterLinked InRedditWechat Abstract This chapter examines the relation between the plastic deformation and cell response on the austenitic 316L stainless steel samples, which were deformed by tensile loading up to 5 different strains: 5, 15, 25, 35 and 60% in an experiment. The specimens were ground with 400, 800, 1200 and 2500 grit SiC papers, and polished with the diamond abrasives with varied particle sizes. After completing the surface analyses, the steel samples were sterilized with an autoclave and each sample was placed into one well in a 24-well tissue culture plate (Costar). Then brain tumor and fibroblast cells were seeded on each well containing 1 ml growth medium and were incubated. The microscopy investigations of the implant surface in parallel with the cell response showed that the plastic deformation induced micro-deformation mechanisms improved the cell viability, attachment and spreading of the brain tumor cells, particularly by distorting the surface topography and enhancing the surface roughness. Surface characterization and microscopy analyses showed that increasing plastic deformation significantly altered surface topography by the formation of surface extrusions and grooves, which increased the surface roughness. Citing Literature Processing, Properties, and Design of Advanced Ceramics and Composites II: Ceramic Transactions, Volume 261 RelatedInformation
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