Portal de Periódicos da CAPES

Treatment challenges in and outside a network setting: Head and neck cancers

2018; Elsevier BV; Volume: 45; Issue: 1 Linguagem: Inglês

10.1016/j.ejso.2018.02.007

1532-2157

Ester Orlandi, Salvatore Alfieri, Christian Simon, Annalisa Trama, Lisa Licitra, Monika Hackl, E. Van Eycken, Kris Henau, Nadya Dimitrova, Mario Sekerija, Ladislav Dušek, Margit Mägi, Nea Malila, Maarit K. Leinonen, Michel Velten, Xavier Troussard, Véronique Bouvier, Anne‐Valérie Guizard, Anne–Marie Bouvier, Patrick Arveux, Marc Maynadié, Anne-Sophie Woronoff, Michel Robaszkiewic, Isabelle Baldi, Alain Monnereau, Brigitte Tretarre, Marc Colonna, F. Molinié, Simona Bara, Claire Schvartz, Bénédicte Lapôtre-Ledoux, Pascale Grosclaude, Roland Stabenow, Sabine Luttmann, Alice Nennecke, Jutta Engel, Gabriele Schubert-Fritschle, Jan Heidrich, Bernd Holleczek, Jón G. Jónasson, Kerri M. Clough‐Gorr, Harry Comber, Guido Mazzoleni, Adriano Giacomin, Antonella Sutera Sardo, Alessandr Barchielli, Diego Serraino, Roberta De Angelis, Sandra Mallone, Andrea Tavilla, Daniela Pierannunzio, Silvia Rossi, Mariano Santaquilani, Arnold Knijn, Fabio Pannozzo, Valerio Gennaro, Lucia Benfatto, Paolo Ricci, M. Autelitano, Gianbattista Spagnoli, Mario Fusco, Mario Usala, Francesco Vitale, Maria Michiara, ­Rosario ­Tumino, Lucìa Mangone, Fabio Falcini, Stefano Ferretti, Rosa Angela Filiberti, Enza Marani, Arturo Iannelli, Flavio Sensi, Silvano Piffer, Maria Gentilini, Anselmo Madeddu, Antonio Ziino, Sergio Maspero, Pina Candela, Fabrizio Stracci, Giovanna Tagliabue, Massimo Rugge, Annalisa Trama, Gemma Gatta, Laura Botta, Riccardo Capocaccia, Santa Pildava, Giedrė Smailytė, Neville Calleja, Tom Børge Johannesen, Jadwiga Rachtan, Stanisław Góźdż, Jerzy Błaszczyk, Kamila Kępska, G. Forjaz de Lacerda, Maria Josè Bento, Ana Luísa P. Miranda, Chakameh Safaei Diba, E. Almar, Nerea Larrañaga, Arantza Lopez de Munain, A. Torrella-Ramos, J.M. Díaz García, Rafael Marcos‐Gragera, Maria Josè Sanchez, Carmen Navarro, Diego Salmerón, Conchi Moreno-Iribas, Jaume Galcerán, Marià Carulla, Seyed Mohsen Mousavi, Christine Bouchardy, Silvia M. Ess, Andrea Bordoni, Isabelle Konzelmann, Jem Rashbass, Anna Gavin, David Brewster, Dyfed Huws, Otto Visser, Magdalena Bielska-Lasota, Maja Primic‐Žakelj, Ian Kunkler, E Benhamou,

Head and Neck Surgical Oncology

Head and neck cancer (HNC) is a rare disease that can affect different sites and is characterized by variable incidence and 5-year survival rates across Europe. Multiple factors need to be considered when choosing the most appropriate treatment for HNC patients, such as age, comorbidities, social issues, and especially whether to prefer surgery or radiation-based protocols. Given the complexity of this scenario, the creation of a highly specialized multidisciplinary team is recommended to guarantee the best oncological outcome and prevent or adequately treat any adverse effect. Data from literature suggest that the multidisciplinary team-based approach is beneficial for HNC patients and lead to improved survival rates. This result is likely due to improved diagnostic and staging accuracy, a more efficacious therapeutic approach and enhanced communication across disciplines. Despite the benefit of MTD, it must be noted that this approach requires considerable time, effort and financial resources and is usually more frequent in highly organized and high-volume centers. Literature data on clinical research suggest that patients treated in high-accrual centers report better treatment outcomes compared to patients treated in low-volume centers, where a lower radiotherapy-compliance and worst overall survival have been reported. There is general agreement that treatment of rare cancers such as HNC should be concentrated in high volume, specialized and multidisciplinary centers. In order to achieve this goal, the creation of international collaboration network is fundamental. The European Reference Networks for example aim to create an international virtual advisory board, whose objectives are the exchange of expertise, training, clinical collaboration and the reduction of disparities and enhancement of rationalize migration across Europe. The purpose of our work is to review all aspects and challenges in and outside this network setting planned for the management of HNC patients.