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BIBTEX RIS

Phase 1 trial of vamorolone, a first-in-class steroid, shows improvements in side effects via biomarkers bridged to clinical outcomes

2018; Elsevier BV; Volume: 134; Linguagem: Inglês

10.1016/j.steroids.2018.02.010

ISSN

1878-5867

Autores

Eric P. Hoffman, Valerie Riddle, Maxime A. Siegler, Daniel Dickerson, Miroslav Bačkonja, William G. Kramer, Kanneboyina Nagaraju, Heather Gordish‐Dressman, Jesse M. Damsker, John M. McCall,

Tópico(s)

Hormonal Regulation and Hypertension

Resumo

Glucocorticoid drugs are highly effective anti-inflammatory agents, but chronic use is associated with extensive pharmacodynamic safety concerns that have a considerable negative impact on patient quality of life.

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