Portal de Periódicos da CAPES

Impact of physical exercise in cancer survivors during and after antineoplastic treatments

2018; Impact Journals LLC; Volume: 9; Issue: 17 Linguagem: Inglês

10.18632/oncotarget.24456

1949-2553

Martina Ferioli, Giorgio Zauli, Alberto M. Martelli, Marco Vitale, James A. McCubrey, Simona Ultimo, Silvano Capitani, Luca M. Neri,

Cancer Treatment and Pharmacology

// Martina Ferioli 1 , Giorgio Zauli 1 , Alberto M. Martelli 2 , Marco Vitale 3, 4 , James A. McCubrey 5 , Simona Ultimo 1 , Silvano Capitani 1 and Luca M. Neri 1 1 Department of Morphology, Surgery and Experimental Medicine, University of Ferrara, Ferrara, Italy 2 Department of Biomedical and Neuromotor Sciences, University of Bologna, Bologna, Italy 3 Department of Medicine and Surgery, University of Parma, Parma, Italy 4 CoreLab, Azienda Ospedaliero-Universitaria di Parma, Parma, Italy 5 Department of Microbiology and Immunology, Brody School of Medicine, East Carolina University, Greenville, NC, USA Correspondence to: Luca M. Neri, email: luca.neri@unife.it Silvano Capitani, email: silvano.capitani@unife.it Keywords: cancer survivors; cancer treatments; psycho-physical symptoms; physical exercise; physical activity treatments Received: December 17, 2017 Accepted: January 23, 2018 Published: February 08, 2018 ABSTRACT Cancer patients experience symptoms and adverse effects of treatments that may last even after the end of treatments. Exercise is a safe, non-pharmacological and cost-effective therapy that can provide several health benefits in cancer patient and survivors, reducing cancer symptoms and cancer treatment side effects. The purpose of this review is to describe how the physical exercise is capable to reduce cancer symptoms and cancer treatment side effects. We realized a pragmatic classification of symptoms, dividing them into physical, psychological and psycho-physical aspects. For each symptom we discuss causes, therapies, we analyse the effects of physical exercise and we summarize the most effective type of exercise to reduce the symptoms. This review also points out what are the difficulties that patients and survivors face during the practice of physical activity and provides some solutions to overcome these barriers. Related to each specific cancer, it emerges that type, frequency and intensity of physical exercise could be prescribed and supervised as a therapeutic program, like it occurs for the type, dose and duration of a drug treatment.