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The Bladder Utility Symptom Scale: A Novel Patient Reported Outcome Instrument for Bladder Cancer

2018; Lippincott Williams & Wilkins; Volume: 200; Issue: 2 Linguagem: Inglês

10.1016/j.juro.2018.03.006

1527-3792

Nathan Perlis, Murray Krahn, K. Boehme, Shabbir M.H. Alibhai, Munir Jamal, Antonio Finelli, Srikala S. Sridhar, Peter Chung, R. Gandhi, Jennifer M. Jones, George Tomlinson, Karen E. Bremner, Girish S. Kulkarni,

Esophageal Cancer Research and Treatment

No AccessJournal of UrologyAdult Urology1 Aug 2018The Bladder Utility Symptom Scale: A Novel Patient Reported Outcome Instrument for Bladder Cancer Nathan Perlis, Murray D. Krahn, Kirstin E. Boehme, Shabbir M.H. Alibhai, Munir Jamal, Antonio Finelli, Srikala S. Sridhar, Peter Chung, Rushi Gandhi, Jennifer Jones, George Tomlinson, Karen E. Bremner, and Girish Kulkarni Nathan PerlisNathan Perlis More articles by this author , Murray D. KrahnMurray D. Krahn More articles by this author , Kirstin E. BoehmeKirstin E. Boehme More articles by this author , Shabbir M.H. AlibhaiShabbir M.H. Alibhai More articles by this author , Munir JamalMunir Jamal More articles by this author , Antonio FinelliAntonio Finelli More articles by this author , Srikala S. SridharSrikala S. Sridhar More articles by this author , Peter ChungPeter Chung More articles by this author , Rushi GandhiRushi Gandhi More articles by this author , Jennifer JonesJennifer Jones More articles by this author , George TomlinsonGeorge Tomlinson More articles by this author , Karen E. BremnerKaren E. Bremner More articles by this author , and Girish KulkarniGirish Kulkarni More articles by this author View All Author Informationhttps://doi.org/10.1016/j.juro.2018.03.006AboutFull TextPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookLinked InTwitterEmail Abstract Purpose: Health related quality of life is important in bladder cancer care and clinical decision making because patients must choose between diverse treatment modalities with unique morbidities. A patient reported outcome measure of overall health related quality of life for bladder cancer regardless of disease severity and treatment could benefit clinical care and research. Materials and Methods: Prospective questionnaire development was completed in 3 parts. In study 1 the BUSS (Bladder Utility Symptom Scale) questions were created by experts using a conceptual framework of bladder cancer health related quality of life generated through patient focus groups. In study 2 patients with bladder cancer, including those treated with surgery, radiation and chemotherapy, completed the BUSS and 5 health related quality of life instruments at baseline and 4 weeks to assess validity and test-retest reliability. External validity was then explored in study 3 by administering the BUSS to 578 patients online and at clinics. Construct validity was assessed by whole and subscale Spearman rank correlations, and by comparisons of BUSS scores across known groups. Results: The BUSS had high whole scale correlation with the FACT-Bl (Functional Assessment of Cancer Therapy-Bladder) (rs = 0.82, p <0.0001) and substantial to high subscale correlations with the EQ-5D™-3L (EuroQol 5 Dimensions Questionnaire-3 Levels) (eg emotional well-being rs = 0.69, p <0.0001). BUSS scores were lower in patients with comorbidity and advanced disease. Cognitive debriefing and the 94% completion rate suggested good comprehensibility. There was excellent test-retest reliability (ICC = 0.79). Limitations included an extended time from diagnosis in many patients. Conclusions: The BUSS is a reliable and valid patient reported outcome instrument for health related quality of life in all patients with bladder cancer regardless of the treatment received or the stage of disease. References 1 : Health related quality of life after radical cystectomy and urinary diversion for bladder cancer: a systematic review and critical analysis of the literature. J Urol2005; 173: 1318. 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Google Scholar 28 : Cancer patients seeking a second surgical opinion: results of a study on motives, needs, and expectations. J Clin Oncol2003; 21: 1492. Google Scholar © 2018 by American Urological Association Education and Research, Inc.FiguresReferencesRelatedDetailsCited byChang S (2020) Re: Assessment of Quality of Life, Information, and Supportive Care Needs in Patients with Muscle and Non-Muscle Invasive Bladder Cancer across the Illness TrajectoryJournal of Urology, VOL. 204, NO. 2, (385-385), Online publication date: 1-Aug-2020. Volume 200Issue 2August 2018Page: 283-291Supplementary Materials Advertisement Copyright & Permissions© 2018 by American Urological Association Education and Research, Inc.Keywordspatient reported outcome measuresquality of lifeurinary bladder neoplasmsneoplasm metastasispatient health questionnaireMetricsAuthor Information Nathan Perlis More articles by this author Murray D. Krahn More articles by this author Kirstin E. Boehme More articles by this author Shabbir M.H. Alibhai More articles by this author Munir Jamal More articles by this author Antonio Finelli More articles by this author Srikala S. Sridhar More articles by this author Peter Chung More articles by this author Rushi Gandhi More articles by this author Jennifer Jones More articles by this author George Tomlinson More articles by this author Karen E. Bremner More articles by this author Girish Kulkarni More articles by this author Expand All Advertisement PDF downloadLoading ...