Artigo Acesso aberto Produção Nacional Revisado por pares

First description of clonal lineage type II (genotype #1) of Toxoplasma gondii in abortion outbreak in goats

2018; Elsevier BV; Volume: 188; Linguagem: Inglês

10.1016/j.exppara.2018.03.008

ISSN

1090-2449

Autores

Júnior Mário Baltazar de Oliveira, Jonatas Campos de Almeida, Renata Pimentel Bandeira de Melo, Luiz Daniel de Barros, João Luís Garcia, Müller Ribeiro-Andrade, Wagnner José Nascimento Porto, Javier Regidor‐Cerrillo, Luís Miguel Ortega-Mora, Andréa Alice da Fonseca Oliveira, Rinaldo Aparecido Mota,

Tópico(s)

Sex work and related issues

Resumo

The purpose of this study was to perform genotypic characterization and to evaluate the virulence of Toxoplasma gondii obtained from aborted fetuses in an abortion outbreak in goats from northeastern Brazil. Brain samples from 32 fetuses were submitted to mouse bioassay for T. gondii isolation. Two isolates were obtained and subjected to genotypic characterization. Isolate virulence was evaluated using murine model in different doses (from 105 to 101 tachyzoites/mL). In genotyping, both isolates were classified as clonal lineage type II (genotype #1 ToxoDB) and showed to be virulent for mice. This is the first description of genotype #1 in cases of goat abortion, showing the circulation of virulent T. gondii isolate producing reproductive disorders in pregnant goat.

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