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Is the recent increment in attributable deaths to type-2 diabetes (T2D) associated with the latest chikungunya outbreak in a major epidemic area in Brazil?

2018; Brazilian Society of Tropical Medicine; Volume: 51; Issue: 1 Linguagem: Inglês

10.1590/0037-8682-0440-2017

ISSN

1678-9849

Autores

Luciano Pamplona de Góes Cavalcanti, Sara Mendes D’angelo, Daniele Rocha Queiróz Lemos, Francisca Kalline de Almeida Barreto, André M. Siqueira, Fábio Miyajima,

Tópico(s)

Viral Infections and Outbreaks Research

Resumo

Chikungunya virus (CHIKV) can negatively influence outcomes in patients with pre-existing conditions. We investigated the association between the recent CHIKV outbreak and increased type 2 diabetes (T2D)-attributable deaths.Monthly averages of T2D-attributable deaths between 2001 and 2016 were determined and compared to the equivalent data for 2017 and the recent CHIKV outbreak.CHKV outbreak peaked in April 2017 with 4,394.4 cases/100,000 inhabitants, while T2D-attributable deaths in the same period increased by 35.2%.T2D-attributable deaths significantly increased compared to the previous data, which overlapped with CHIKV incidence. The pathophysiology of this association warrants further investigations.

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