Portal de Periódicos da CAPES

Diagnosis and management of asymptomatic bacteriuria in kidney transplant recipients: a survey of current practice in Europe

2018; Oxford University Press; Volume: 33; Issue: 9 Linguagem: Inglês

10.1093/ndt/gfy078

1460-2385

Julien Coussement, Umberto Maggiore, Oriol Manuel, Anne Scemla, Francisco López‐Medrano, Evi Nagler, José María Aguado, Daniel Abramowicz, Brigitte Adams, Caroline Agnelli, Oana Ailioaie, Hamdi Akan, Lucile Amrouche, Amado Andrés, Dany Anglicheau, Paul Arnouts, Marije C. Baas, Cristian Balgradean, Bert Bammens, Yuri Battaglia, Thomas Baudoux, I.M. Berto, Isabelle Binet, Claus Bistrup, Renzo Bonofiglio, Jean‐Louis Bosmans, Yassine Bouatou, Nicolas Bouvier, Philippe Braconnier, Edwin Bredewold, Nilüfer Broeders, Philippe Brunet, Matthias Büchler, Klemens Budde, Fanny Buron, Stéphane Burtey, Andrea Buscaroli, Stefan Büttner, Catherine Byrne, Rossana Caldara, Élisabeth Cassuto, Concetta Catalano, Guilhem Cavaillé, Alice Corbel, Lionel Couzi, Marta Crespo, Sunil Daga, Frederic Debellé, Ivana Dedinská, Paul A. Devine, Michael Dickenmann, Max Dratwa, Ľuboš Drgoňa, Magdalena Durlik, Maria Francesca Egidi, P Errasti, Isabelle Étienne, María Carmen Fariñas, Thomas Fehr, Mario Fernández‐Ruiz, Paraskevi Founta, Konstantinos Fourtounas, Eleni Frangou, Luc Frimat, Lucrezia Furian, Maria Garjau, Valérie Garrigue, Philippe Gatault, Colin Geddes, Marie-Paule Gerlinger, E. Gheuens, Lidia Ghisdal, Paul Gibbs, Magali Giral, Sophie Girerd, Déla Golshayan, Athina Gompou, Paolo Grossi, Gabriele Guglielmetti, Luís Guirado, Karine Hadaya, Marc Hazzan, Mark F. Helbert, Rachel Hellemans, Katharina Heller, Uwe Heemann, Manu Henckes, Domingo Hernández, Alexandre Hertig, C Hiesse, Luuk B. Hilbrands, Rachel Hilton, Cédric Hirzel, Juan Pablo Horcajada, Jean‐Michel Hougardy, Uyen Huynh‐Do, Alma Idrizi, Khalid Ismaïli, Carlos Jiménez, Noémie Jourde‐Chiche, Nassim Kamar, Hannah Kaminski, Julia Kanter, Alexandre Karras, Delphine Kemlin, Petar Kes, M. Kianda, Marian Klinger, Simon Knight, Irene Koneth, Anita Krrashi, Dirk Kuypers, Anne‐Lyse Langlois, Philippe Lang, Ricardo Lauzurica, Alaín Le Moine, David Lebeaux, Christophe Legendre, Anne Lemy, Òscar Len, Vassilios Liakopoulos, Monika Lichodziejewska‐Niemierko, Maria Belen Loeches Yague, Kai Lopau, Philippe Madhoun, Maria Magott-Procelewska, Shafi Malik, Anna Montero, Francesco Marchini, Alessandra Marega, Christophe Mariat, Patrick B. Mark, Pierre‐Yves Martin, Leyre Martín Rodríguez, Paloma Leticia Martín-Moreno, Annick Massart, Marie Matignon, Stéphane Maurel, Auxiliadora Mazuecos, Christina Melexopoulou, Edoardo Melilli, Esperanza Merino, Enisa Mešić, Piergiorgio Messa, Magdalena Michalak, Enrico Minetti, G Miserlis, Miguel Montejo, Diego Moriconi, C. Mottola, Georges Mourad, Thomas Mueller, Patricia Muñóz, Alexander Nabokow, Maarten Naesens, M. Nikodimopoulou, Rainer Oberbauer, María Olmedo, Jonathon Olsburgh, Gabriel C. Oniscu, Lara Aygen Øzbay, Alessandra Palmisano, Αikaterini Papagianni, Marios Papasotiriou, Angelica Parodi, Rob G Parry, Julio Pascual, Isabel Flores, María José Pérez‐Sáez, Licia Peruzzi, Camille Petit-Hoang, Paul J. Phelan, Évangéline Pillebout, Giovanni Piotti, Lissa Pipeleers, Christos Pleros, Joyce Popoola, R. Pretagostini, Erasmia Psimenou, Josep Puig, Cédric Rafat, Silvie Rajnochová­ Bloudíčková, Irena Rambabova Bushljetikj, Marina Ratković, Dolores Redondo‐Pachón, Tomáš Reischig, Thomas Robert, María Luisa Rodríguez Ferrero, Merita Rroji, Przemysław Rutkowski, Alicja Rydzewska–Rosołowska, Núria Sabé, Dil Sahali, Bernd Salzberger, Rafael San Juan, Beatriz Sobrino, Silvio Sandrini, Lídia Santos, Roxana Sava, Stefan Schaub, Johan Schikowski, Betoul Schvartz, Urban Sester, José Tiago Silva, Renaud Snanoudj, Danio Somenzi, Søren Schwartz Sørensen, Vibeke Rømming Sørensen, Georgios Spanos, Jürg Steiger, Barbara Suwelack, Eleni Theodoropoulou, Éric Thervet, Stefan Thorban, Giuliana Tognarelli, Yasmina Tournay, Leïla Tricot, Patrizia Tulissi, Henri Vacher-Coponat, Maricela Valerio, Wilbert A.G. van der Meijden, Henk van Hamersvelt, Steven Van Laecke, Alain Vandivinit, Raymond Vanholder, Massimiliano Veroux, Ondřej Viklický, Emanuela Vigo, Claudio Viscoli, Bruno Watschinger, Laurent Weekers, Matthew Welberry Smith, Karl Martin Wissing, Nereida Zeneli, Angelos Zervos, Lada Zibar, Julien Zuber, Bianca Zukunft,

Metabolism and Genetic Disorders

Asymptomatic bacteriuria is frequent in kidney transplant recipients (KTRs). However, there is no consensus on diagnosis or management. We conducted a European survey to explore current practice related to the diagnosis and management of asymptomatic bacteriuria in adult KTRs.A panel of experts from the European Renal Association-European Dialysis Transplant Association/Developing Education Science and Care for Renal Transplantation in European States working group and the European Study Group for Infections in Compromised Hosts of the European Society of Clinical Microbiology and Infectious Diseases designed this cross-sectional, questionnaire-based, self-administered survey. Invitations to participate were e-mailed to European physicians involved in the care of KTRs.Two hundred and forty-four participants from 138 institutions in 25 countries answered the survey (response rate 30%). Most participants [72% (176/244)] said they always screen for asymptomatic bacteriuria in KTRs. Six per cent (15/240) reported never treating asymptomatic bacteriuria with antibiotics. When antimicrobial treatment was used, 24% of the participants (53/224) said they would start with empirical antibiotics. For an episode of asymptomatic bacteriuria caused by a fully susceptible microorganism and despite no contraindications, a majority of participants (121/223) said they would use a fluoroquinolone (n = 56), amoxicillin/clavulanic acid (n = 38) or oral cephalosporins (n = 27).Screening for and treating asymptomatic bacteriuria are common in KTRs despite uncertainties around the benefits and harms. In an era of antimicrobial resistance, further studies are needed to address the diagnosis and management of asymptomatic bacteriuria in these patients.