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Effects of 8-hour time restricted feeding on body weight and metabolic disease risk factors in obese adults: A pilot study

2018; IOS Press; Volume: 4; Issue: 4 Linguagem: Inglês

10.3233/nha-170036

2451-9502

Kelsey Gabel, Kristin K. Hoddy, Nicole Haggerty, Jeehee Song, Cynthia M. Kroeger, John F. Trepanowski, Satchidananda Panda, Krista A Varady,

Circadian rhythm and melatonin

Time restricted feeding decreases energy intake without calorie counting and may be a viable option for weight loss. However, the effect of this diet on body weight in obese subjects has never been examined.This study investigated the effects of 8-h time restricted feeding on body weight and metabolic disease risk factors in obese adults.Obese subjects (n = 23) participated in an 8-h time restricted feeding intervention (ad libitum feeding between 10:00 to 18:00 h, water fasting between 18:00 to 10:00 h) for 12 weeks. Weight loss and other outcomes were compared to a matched historical control group (n = 23).Body weight and energy intake decreased in the time restricted group (-2.6% ± 0.5; -341 ± 53 kcal/d) relative to controls over 12 weeks (P < 0.05). Systolic blood pressure decreased in the time restricted feeding group (-7 ± 2 mm Hg) versus controls (P < 0.05). Fat mass, lean mass, visceral fat mass, diastolic blood pressure, LDL cholesterol, HDL cholesterol, triglycerides, fasting glucose, fasting insulin, HOMA-IR, and homocysteine were not significantly different from controls after 12 weeks (no group×time interaction).These findings suggest that 8-h time restricted feeding produces mild caloric restriction and weight loss, without calorie counting. It may also offer clinical benefits by reducing blood pressure.