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A pilot study of a natural fiber complex IQP-AK-102’s effect in reducing appetite and caloric intake in overweight subjects

2018; Volume: 6; Issue: 2 Linguagem: Inglês

10.30918/ampr.62.18.012

2354-2152

Ralf Uebelhack, Udo Bongartz, Barbara Grube, JooLian Khoo, Pee-Win Chong,

Microbial Metabolites in Food Biotechnology

A proprietary fiber complex, IQP-AK-102, consisting of glucomannan, kappa-carrageenan and xanthan gum, has been shown to reduce body weight in a double-blind, randomised, placebo-controlled clinical trial.It was postulated that IQP-AK-102 promotes weight loss through enhancing satiety, increasing gastric distension and delaying gastric emptying.Therefore, the aim of this study was to examine if appetite reduction through above-mentioned mechanisms is underlying the efficacy of IQP-AK-102 for body weight loss.Thirty-six healthy overweight adults (BMI 25-30 kg/m 2 ) were administered 2 capsules of IQP-AK-102 three times daily for 4 weeks, after a 2-week run-in phase.Visual analogue scales (VAS) and Haber (hunger/satiety) scale were used to evaluate the appetite sensation.All measurements were assessed 3 days a week during the run-in phase as well as in the first and last week of the treatment period.The scales were completed before breakfast (at time -30 and 0 min) and after breakfast (at time 15, 30, 45, 60, 90, 120 and 180 min).Additionally, food intake was also recorded in a food diary.The appetite evaluation study showed that IQP-AK-102 reduced both the appetite sensation and the mean daily caloric intake significantly after 1 week and 4 weeks of intake.IQP-AK-102 was well tolerated throughout the study duration, with no product related adverse effects reported.These results suggest that IQP-AK-102 reduces appetite and caloric intake and thus, can be considered a natural and safe intervention for promoting weight loss.