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Aquaporins in cancer development: opportunities for bioinorganic chemistry to contribute novel chemical probes and therapeutic agents

2018; Oxford University Press; Volume: 10; Issue: 5 Linguagem: Inglês

10.1039/c8mt00072g

1756-591X

Brech Aikman, Andreia de Almeida, Samuel M. Meier, Angela Casini,

Membrane-based Ion Separation Techniques

Metal ions and complexes can interfere with the transcellular water flow but also with the cellular transport of glycerol and hydrogen peroxide, via inhibition of the ubiquitous aquaporin channels.