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BIBTEX RIS

Use of Urea Wash ELISA to Distinguish Zika and Dengue Virus Infections

2018; Centers for Disease Control and Prevention; Volume: 24; Issue: 7 Linguagem: Inglês

10.3201/eid2407.171170

ISSN

1080-6059

Autores

Wen-Yang Tsai, Han‐Ha Chai, Jasmine Tyson, Carlos Brites, Jih‐Jin Tsai, Célia Pedroso, Jan Felix Drexler, Ángel Balmaseda, Eva Harris, Wei-Kung Wang,

Tópico(s)

Malaria Research and Control

Resumo

Serologic testing remains crucial for Zika virus diagnosis. We found that urea wash in a Zika virus nonstructural protein 1 IgG ELISA distinguishes secondary dengue virus infection from Zika virus infection with previous dengue (sensitivity 87.5%, specificity 93.8%). This test will aid serodiagnosis, serosurveillance, and monitoring of Zika complications in dengue-endemic regions.

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