Portal de Periódicos da CAPES

Artigo Acesso aberto Produção Nacional Revisado por pares

BIBTEX RIS

INFLUÊNCIA DO MÉTODO EXTRATIVO NO TEOR DE FLAVONOIDES DE Cnidoscolus quercifolius POHL (EUPHORBIACEAE) E ATIVIDADE ANTIOXIDANTE

2018; Brazilian Chemical Society; Linguagem: Inglês

10.21577/0100-4042.20170236

1678-7064

Daniel Joel Petroche Torres, Emanuella Chiara Valença Pereira, Pedrita Alves Sampaio, Nathália Andrezza Carvalho de Souza, Christiane Adrielly Alves Ferraz, Ana Paula de Oliveira, Celuane Alves Moura, Jackson Roberto Guedes da Silva Almeida, Pedró José Rolim Neto, Raimundo Gonçalves de Oliveira Júnior, Larissa Araújo Rolim,

Phytochemistry Medicinal Plant Applications

Cnidoscolus quercifolius Pohl is a Brazilian medicinal plant from Caatinga biome and possesses several pharmacological properties.Phytochemical investigations have attributed some of these properties to the presence of flavonoids.In this paper, we report the influence of the extraction process on the flavonoid content obtained from leaves of C. quercifolius and its antioxidant activity.A factorial design 2² was performed, using temperature and agitation as independent variables.Qualitative and quantitative analyzes of the extracts were performed by HPLC-DAD.Rutin and apigenin were identified in the extracts and chosen as analytical markers.Pareto chart and Surface response plots suggested that rutin content was increased up to 3.93 times when temperature was employed during the extraction process.However, apigenin content was significantly reduced in the method whose temperature or agitation were used (p<0.05).A higher antioxidant activity was observed in extracts whose rutin extraction was favored, suggesting that this flavonoid contributes at least in part to the antioxidant potential of the species.