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Severe Plasmodium ovale malaria complicated by acute respiratory distress syndrome in a young Caucasian man

2018; BioMed Central; Volume: 17; Issue: 1 Linguagem: Inglês

10.1186/s12936-018-2289-2

1475-2875

Alessandra D’Abramo, Saba Gebremeskel Teklè, Marco Iannetta, Laura Scorzolini, Alessandra Oliva, Maria Grazia Paglia, Angela Corpolongo, Emanuele Nicastri,

Mosquito-borne diseases and control

Although Plasmodium ovale is considered the cause of only mild malaria, a case of severe malaria due to P. ovale with acute respiratory distress syndrome is reported. A 37-year old Caucasian man returning home from Angola was admitted for ovale malaria to the National Institute for Infectious Diseases Lazzaro Spallanzani in Rome, Italy. Two days after initiation of oral chloroquine treatment, an acute respiratory distress syndrome was diagnosed through chest X-ray and chest CT scan with intravenous contrast. Intravenous artesunate and oral doxycycline were started and he made a full recovery. Ovale malaria is usually considered a tropical infectious disease associated with low morbidity and mortality. However, severe disease and death have occasionally been reported. In this case clinical failure of oral chloroquine treatment with clinical progression towards acute respiratory distress syndrome is described.