Acral lentiginous melanoma
2018; Elsevier BV; Volume: 391; Issue: 10137 Linguagem: Inglês
10.1016/s0140-6736(18)31071-7
ISSN1474-547X
Autores Tópico(s)Cutaneous lymphoproliferative disorders research
ResumoA 55-year-old woman presented with a non-healing, painless pigmented macule with a superficial ulceration on the left planta, which she said had been there for 6 months. She could not recall any history of trauma and did not report any family history of cutaneous diseases. On physical examination, an irregular pigmented macule with a superficial ulceration and brown haemorrhagic crusts was observed on the left plantar near the heel (figures). A skin biopsy showed a malignant melanoma and immunohistochemical examination of biopsied tissue sections showed positive staining for melanoma associated antigens using the antibodies HMB-45, Melan-A, and S100. The patient was diagnosed with an acral lentiginous melanoma (ALM). She underwent a wide local excision with a sufficiently large margin from the lesion's border. A sentinel lymph node biopsy of the inguinal nodes was negative. Fortunately, there was no evidence of recurrence during 5 years of follow-up.
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