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Influence of Probiotics Administration on Gut Microbiota Core

2018; Lippincott Williams & Wilkins; Volume: 52; Issue: Supplement 1 Linguagem: Inglês

10.1097/mcg.0000000000001064

1539-2031

Silvia Falcinelli, Ana Rodiles, Azadeh Hatef, Simona Picchietti, Lina Cossignani, Daniel L. Merrifield, Suraj Unniappan, Oliana Carnevali,

Diet, Metabolism, and Disease

An increasing number of studies has shown that dietary probiotics exert beneficial health effects in both humans and animals. It is well established that gut microbiota play a pivotal role in regulating host metabolism, and a growing number of studies has elucidated that probiotics positively interfere with gut microbiota. Accumulating evidence shows that probiotics, through their metabolic activity, produce metabolites that in turn contribute to positively affect host physiology. For these reasons, probiotics have shown significant potential as a therapeutic tool for a diversity of diseases, but the mechanisms through which probiotics act has not been fully elucidated yet. The goal of this review was to provide evidence on the effects of probiotics on gut microbiota changes associated with host metabolic variations, specifically focusing on feed intake and lipid and glucose metabolism. In addition, we review probiotic interaction with the gut microbiota. The information collected here will give further insight into the effects of probiotics on the gut microbiota and their action on metabolite release, energy metabolism, and appetite. This information will help to improve knowledge to find better probiotic therapeutic strategies for obesity and eating disorders.