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BIBTEX RIS

A De Novo Mouse Model of C11orf95-RELA Fusion-Driven Ependymoma Identifies Driver Functions in Addition to NF-κB

2018; Cell Press; Volume: 23; Issue: 13 Linguagem: Inglês

10.1016/j.celrep.2018.04.099

ISSN

2639-1856

Autores

Tatsuya Ozawa, Sonali Arora, Frank Szulzewsky, Gordana Juric‐Sekhar, Yoshiteru Miyajima, Hamid Bolouri, Yoshie Yasui, Jason Barber, Robert Kupp, James Dalton, Terreia S. Jones, Mitsutoshi Nakada, Toshihiro Kumabe, David W. Ellison, Richard J. Gilbertson, Eric C. Holland,

Tópico(s)

Immune cells in cancer

Resumo

The majority of supratentorial ependymomas (ST-ependymomas) have few mutations but frequently display chromothripsis of chromosome 11q that generates a fusion between C11orf95 and RELA (RELA

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