Produção Nacional
Revisado por pares
Combination therapy with liposomal amphotericin b (ambisome), n-methylglucamine antimoniate (glucantime), and pentamidine isethionate in a refractory visceral leishmaniasis case
2018; Brazilian Society of Tropical Medicine; Volume: 51; Issue: 3 Linguagem: Inglês
10.1590/0037-8682-0398-2017
ISSN1678-9849
AutoresMaria Antonia Ferreira Gomes, Lana Lira Cantidio de Medeiros, Fernanda Paula Dantas Lobo, Nathália Rayane Silva Wanderley, Ana Paula Rodrigues Matos, Tácito do Nascimento Jácome, Maria Goretti Lins Monteiro, Kléber Giovanni Luz,
Tópico(s)Synthesis and Characterization of Heterocyclic Compounds
ResumoVisceral leishmaniasis is a systemic disease that is potentially severe and endemic in Brazil. It clinically manifests as fever, weight loss, swelling, hepatosplenomegaly, paleness, and edema. In this study, we discuss a case of a 1-year-old child diagnosed with refractory visceral leishmaniasis after being treated with liposomal amphotericin B in two distinct occasions. Considering the persistent clinical features and weak response to conventional treatment, a combination therapy with liposomal amphotericin B (ambisome), n-methylglucamine antimoniate (glucantime), and pentamidine isethionate was initiated, and response to treatment was good.
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