Chemical Composition and Molecular Parameters of Purified Plasma Proteins
1960; Elsevier BV; Linguagem: Inglês
10.1016/b978-1-4832-2810-5.50012-8
AutoresRobert A. Phelps, Frank W. Putnam,
Tópico(s)Iron Metabolism and Disorders
ResumoThis chapter discusses the delineation of the purified plasma proteins, and the chemical composition and molecular parameters of plasma proteins. As fluctuating components of a dynamic, circulating system, the plasma proteins have always defied characterization and purification by any single method. Plasma, as the greatest single source of proteins of widespread interest, has challenged the protein chemist and prompted the development of new fractionation schemes such as the cold-ethanol method, and physical chemical techniques such as boundary and zone electrophoresis. Some plasma proteins such as complement, properdin, erythropoietin, and the isohemagglutinins are best detected by a biological property and have yet to be isolated in reasonably pure and identifiable form. Others such as serum albumin, the α1-acid glycoprotein, and ceruloplasmin are crystallizable and rather sharply definable.
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