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BIBTEX RIS

Clinical and laboratorial features of oral candidiasis in HIV-positive patients

2018; Brazilian Society of Tropical Medicine; Volume: 51; Issue: 3 Linguagem: Inglês

10.1590/0037-8682-0241-2017

1678-9849

Regiane Nogueira Spalanzani, Karine Mattos, Luiza Inahê Marques, Pedro Fernando Diniz Barros, Pamela Iruama Peres Pereira, Anamaria Mello Miranda Paniago, Rinaldo Pôncio Mendes, Marilene Rodrigues Chang,

Oral Health Pathology and Treatment

INTRODUCTION We describe the clinical and laboratorial features of oral candidiasis in 66 HIV-positive patients. METHODS: Polymerase chain reaction-based techniques were performed for differentiation of Candida spp. isolated from patients at a public teaching hospital in Midwest Brazil. RESULTS: Oral lesions, mainly pseudomembranous, were significantly related to higher levels of immunosuppression. Of 45 Candida isolates, 66.7% were C. albicans. Most of the isolates were susceptible to the antifungal drugs tested. CONCLUSIONS: Oral lesions were associated with higher immunosuppression levels. Lower susceptibility to antifungals by non-albicans isolates supports the importance of surveillance studies using susceptibility tests to aid in the treatment.