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The use of a dithiane protected benzoin photolabile safety catch linker for solid-phase synthesis

1997; Elsevier BV; Volume: 38; Issue: 7 Linguagem: Inglês

10.1016/s0040-4039(96)02478-1

1873-3581

Anne Routledge, Chris Abell, Shankar Balasubramanian,

Photochromic and Fluorescence Chemistry

The dithiane protected benzoin group is shown to be a useful safety catch photolabile linker in solid-phase synthesis. Methods for the synthesis, loading, deprotection and photolysis of the linker are described.