Thyroiditis and Acquired Hypothyroidism in Adults
1972; Elsevier BV; Linguagem: Inglês
10.1016/b978-0-08-016628-5.50014-6
AutoresP. A. Bastenie, M. Bonnyns, L. Vanhaelst,
Tópico(s)Growth Hormone and Insulin-like Growth Factors
ResumoThis chapter discusses the clinical features, pathology, immunology, diagnosis, and treatment of thyroiditis and acquired hypothyroidism in adults. Acquired hypothyroidism in adults constitutes a clinical condition with characteristic signs indicating insufficient thyroid hormone secretion. Numerous factors may lie at the root of hypothyroidism. The immediate cause is either a deficit of thyrotropic hormone secretion by the pituitary gland or a primary atrophy of the thyroid. The treatment of hypothyroidism associated with atrophie lymphocytic thyroiditis is no different in principle from the substitution treatment prescribed in other forms of hypothyroidism. However, two aspects of this particular condition should dictate greater caution than is necessary in the treatment of thyroid insufficiency occurring in young subjects after medical or surgical intervention. The first of these aspects is the partial atrophy of the adrenal cortex found in some cases and attaining extreme degrees in Schmidt's syndrome. The administration of small doses of cortisone acetate is advised during the first stage of thyroid treatment. The second aspect is the vascular sclerosis, especially coronary sclerosis, encountered in a large number of patients.
Referência(s)