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EFICÁCIA DO FIPRONIL ORAL NO CONTROLE DE Ctenocephalides felis felis (SIPHONAPTERA: PULICIDAE) E Rhipicephalus sanguineus (ACARI: IXODIDAE) EM CÃES

2012; Sociedade de Medicina Veterinária do Estado do Rio de Janeiro; Volume: 34; Linguagem: Inglês

2527-2179

Raquel M.P.S. Melo, Vanessa Paulino da Cruz Vieira, Pedro Vianna Tavares, Lilian C.S.O. Batista, Milena Batista Carneiro, Thaís Ribeiro Correia, Yara Peluso Cid, Katherina Coumendouros, Fábio Barbour Scott,

Venomous Animal Envenomation and Studies

ABSTRACT. Melo R.M.P.S., Vieira V.P.C., Tavares P.V., Batista L.C.S.O., Carneiro M.B., Correia T.R., Cid Y.P., Coumendouros K. & Scott F.B. [Oral Efficacy of Fipronil in the control of Ctenocephalides felis felis (Siphonaptera: Pulicidae) and Rhipicephalus sanguineus (Acari: Ixodidae) in dogs]. Eficacia oral do fipronil no controle de Ctenocephalides felis felis (Siphonaptera: Pulicidae) e Rhipicephalus sanguineus (Acari: Ixodidae) em caes. Revista Brasileira de Medicina Veterinaria 34(Supl. 1):15-20, 2012. Departamento de Zootecnia, Universidade Federal de Sao Joao Del Rei (UFSJ), Rodovia BR 494, Km 2, Sao Joao Del Rei, MG 36300-000, Brazil. E-mail: raquel@ufsj.edu.br Fipronil has been used worldwide by topic application for control of Ctenocephalides felis felis and Rhipicephalus sanguineus. The efficacy of fipronil administered orally was evaluated against C. felis felis and R. sanguineus in artificially infested dogs. Twenty four Beagle dogs were divided in three treated groups, which received fipronil in gelatin capsules at single oral doses of 2.4 and 6 mg.kg-1 of body weight on day 0, the fourth group was kept as non medicated control. Dogs were infested weekly with 100 fleas and 50 ticks, two days before each assessment. The evaluations were done weekly, counting fleas and ticks using the comb test method, on days +2, +7, +14 and +21. The efficacy data registered for flea control using 2 mg.kg-1 were 100% on day +2 and 83.79% on day +7. Dogs treated with 4 mg.kg-1 showed reductions of 88.34 for day +2 and 67.98% for day +7. Data related to days 14 and 21 for both groups were lower than 60%. Efficacy on animals treated with fipronil at 6 mg.kg-1 orally was 97.88, 95.27, 88.75 and 71.43% on days +2, +7, +14 and +21, respectively. Very low efficacy results were registered against ticks, R. sanguineus: fipronil orally at 2 mg.kg-1 exhibited ef ficacy of 25.35% and 0, dogs treated with 4 mg.kg-1 orally, 29.58% and 0, and animals treated with 6 mg.kg-1 the efficacy were 43.67 and 23.28%, respectively, on days +2 and +7. The data showed that oral administration of 6 mg.kg-1 of fipronil can be effective in controlling flea infestation by C. felis felis in dogs up 14 days, but it is not effective in control of R. sanguineus in dogs.