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Cytokines in aortic dissection

2018; Elsevier BV; Volume: 486; Linguagem: Inglês

10.1016/j.cca.2018.08.005

1873-3492

Tao Zeng, Lei Shi, Qingwei Ji, Ying Shi, Ying Huang, Yu Liu, Jianting Gan, Jun Yuan, Zhengde Lu, Yan Xue, Haiying Hu, Ling Liu, Yingzhong Lin,

Aortic aneurysm repair treatments

Aortic dissection (AD) is one of the most dangerous forms of vascular disease, characterized by endometrial rupture and intramural hematoma formation. Generally, the pathological process is complicated and closely related to the infiltration of inflammatory cells into the aortic wall and apoptosis of vascular smooth muscle cells. Currently, multiple cytokines, including interleukins, interferon, the tumor necrosis factor superfamily, colony stimulating factor, chemotactic factor, growth factor and so on, have all been demonstrated to play a critical role in AD. Additionally, studies of the link between cytokines and AD could deepen our understanding of the disease and may guide future treatment therapies; therefore, this review focuses on the role of cytokines in AD.