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The transcriptional landscape of polyploid wheat

2018; American Association for the Advancement of Science; Volume: 361; Issue: 6403 Linguagem: Inglês

10.1126/science.aar6089

1095-9203

R. H. Ramírez-González, Philippa Borrill, Daniel Lang, Sophie A. Harrington, Jemima Brinton, Luca Venturini, Mark W. Davey, John Jacobs, Frédéric Van Ex, Asher Pasha, Yogendra Khedikar, Stephen J. Robinson, Aron T. Cory, Tobin Florio, Lorenzo Concia, Caroline Juéry, Henk‐jan Schoonbeek, Burkhard Steuernagel, Daoquan Xiang, Christopher J. Ridout, Boulos Chalhoub, Klaus Mayer, Moussa Benhamed, David Latrasse, Abdelhafid Bendahmane, Brande B. H. Wulff, R. Appels, Vijay Tiwari, Raju Datla, Frédéric Choulet, Curtis Pozniak, Nicholas J. Provart, Andrew Sharpe, Etienne Paux, M. Spannagl, Andrea Bräutigam, Cristóbal Uauy, Abraham B. Korol, Andrew Sharpe, Angéla Juhász, Antje Rohde, Arnaud Bellec, Assaf Distelfeld, Bala Anı Akpınar, Beat Keller, Benoît Darrier, Bikram Gill, Boulos Chalhoub, Burkhard Steuernagel, Catherine Feuillet, Chanderkant Chaudhary, Cristóbal Uauy, Curtis Pozniak, Danara Ormanbekova, Daoquan Xiang, David Latrasse, David Swarbreck, Delfina Barabaschi, Dina Raats, E. M. Sergeeva, Е. А. Салина, Etienne Paux, Federica Cattonaro, Frédéric Choulet, Fuminori Kobayashi, Gabriel Keeble‐Gagnère, Gaganpreet Kaur, Gary J. Muehlbauer, George Kettleborough, Guotai Yu, Hana Šimková, Heidrun Gundlach, Hélène Bergès, Hélène Rimbert, Hikmet Budak, Hirokazu Handa, Ian Small, Jan Bartoš, Jane Rogers, Jaroslav Doležel, Jens Keilwagen, Jesse Poland, Joanna Melonek, John Jacobs, Jon Wright, Jonathan D. G. Jones, Juan J. Gutiérrez-González, Kellye Eversole, Kirby T. Nilsen, Klaus Mayer, K. Kanyuka, Kuldeep Singh, Liangliang Gao, Lorenzo Concia, Luca Venturini, Luigi Cattivelli, M. Spannagl, Martin Mascher, Matthew Hayden, Michaël Abrouk, Michaël Alaux, Ming‐Cheng Luo, Miroslav Valárik, Moussa Benhamed, Nisha Singh, Naveen Sharma, Nicolas Guilhot, Nikolai V. Ravin, Nils Stein, Odd-Arne Olsen, O. P. Gupta, Paramjit Khurana, Parveen Chhuneja, Philipp E. Bayer, Philippa Borrill, Philippe Leroy, Philippe Rigault, Pierre Sourdille, Pilar Hernández, Raphaël Flores, Ricardo H. Ramírez-González, Robert C. King, R. E. Knox, R. Appels, Ruonan Zhou, Sean Walkowiak, Sergio Gálvez, Sezgi Biyiklioglu, Shuhei Nasuda, Simen R. Sandve, Smahane Chalabi, Song Weining, Sunish K. Sehgal, Suruchi Jindal, Tatiana Belova, Thomas Letellier, Thomas Wicker, Tsuyoshi Tanaka, Tzion Fahima, Valérie Barbe, Vijay Tiwari, Vinod Kumar, Yifang Tan,

Genetic Mapping and Diversity in Plants and Animals

The coordinated expression of highly related homoeologous genes in polyploid species underlies the phenotypes of many of the world's major crops. Here we combine extensive gene expression datasets to produce a comprehensive, genome-wide analysis of homoeolog expression patterns in hexaploid bread wheat. Bias in homoeolog expression varies between tissues, with ~30% of wheat homoeologs showing nonbalanced expression. We found expression asymmetries along wheat chromosomes, with homoeologs showing the largest inter-tissue, inter-cultivar, and coding sequence variation, most often located in high-recombination distal ends of chromosomes. These transcriptionally dynamic genes potentially represent the first steps toward neo- or subfunctionalization of wheat homoeologs. Coexpression networks reveal extensive coordination of homoeologs throughout development and, alongside a detailed expression atlas, provide a framework to target candidate genes underpinning agronomic traits in wheat.