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BIBTEX RIS

Human T Lymphotropic Virus and Pulmonary Diseases

2018; Frontiers Media; Volume: 9; Linguagem: Inglês

10.3389/fmicb.2018.01879

ISSN

1664-302X

Autores

Ápio Ricardo Nazareth Dias, Luiz Fábio Magno Falcão, Aline Semblano Carreira Falcão, Valéria Marques Ferreira Normando, Juarez Antônio Simões Quaresma,

Tópico(s)

Animal Disease Management and Epidemiology

Resumo

Human T lymphotropic virus type 1 (HTLV-1) is the etiological agent of HTLV-1-associated myelopathy, and adult T cell lymphoma/leukemia (ATL/L). Pulmonary complications such as alveolitis and bronchiectasis were found in individuals who develop TSP/HAM due to chronic inflammation. These individuals showed image anomalies in CT scans and changes in pulmonary function parameters distinctive of pulmonary disease. Furthermore, infected individuals have a greater susceptibility to pulmonary tuberculosis either due to changes in the innate immune response, in asymptomatic carriers, or to an opportunistic disease linked to immunodepression, in individuals who develop ATL/L. This summary addresses the general lack of knowledge regarding the relationship between HTLV-1 and pulmonary diseases and provides direction for future work.

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