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Six-Month Outcomes after Restrictive or Liberal Transfusion for Cardiac Surgery

2018; Massachusetts Medical Society; Volume: 379; Issue: 13 Linguagem: Inglês

10.1056/nejmoa1808561

1533-4406

C. David Mazer, Richard Whitlock, Dean Fergusson, Emilie P. Belley‐Côté, Katherine Connolly, Boris Khanykin, Alexander J. Gregory, Étienne de Médicis, François Martin Carrier, Shay McGuinness, Paul J. Young, Kelly Byrne, Juan Carlos Villar, Alistair Royse, Hilary P. Grocott, Manfred D. Seeberger, Chirag Mehta, François Lellouche, Gregory M. T. Hare, Thomas Painter, Stephen E. Fremes, Summer Syed, Sean M. Bagshaw, Nian Chih Hwang, Colin Royse, Judith E. Hall, David Dai, Nikhil Mistry, Kevin E. Thorpe, Subodh Verma, Peter Jüni, Nadine Shehata,

Cardiac and Coronary Surgery Techniques

We reported previously that, in patients undergoing cardiac surgery who were at moderate-to-high risk for death, a restrictive transfusion strategy was noninferior to a liberal strategy with respect to the composite outcome of death from any cause, myocardial infarction, stroke, or new-onset renal failure with dialysis by hospital discharge or 28 days after surgery, whichever came first. We now report the clinical outcomes at 6 months after surgery.