
March1-dependent modulation of donor MHC II on CD103+ dendritic cells mitigates alloimmunity
2018; Nature Portfolio; Volume: 9; Issue: 1 Linguagem: Inglês
10.1038/s41467-018-05572-z
ISSN2041-1723
AutoresThiago J. Borges, Naoka Murakami, Felipe D. Machado, Ayesha Murshid, Benjamin Lang, Rafael L. Lopes, Laura M. Bellan, Mayuko Uehara, Krist Helen Antunes, María José Pérez‐Sáez, Gabriel Birrane, Priscila Vianna, João Ismael Budelon Gonçalves, Rafael Fernandes Zanin, Jamil Azzi, Reza Abdi, Satoshi Ishido, Jeoung‐Sook Shin, Ana Paula Duarte de Souza, Stuart K. Calderwood, Leonardo V. Riella, Cristina Bonorino,
Tópico(s)Immune Cell Function and Interaction
ResumoIn transplantation, donor dendritic cells (do-DCs) initiate the alloimmune response either by direct interaction with host T cells or by transferring intact donor MHC to host DCs. However, how do-DCs can be targeted for improving allograft survival is still unclear. Here we show CD103
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