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The discovery of Bombali virus adds further support for bats as hosts of ebolaviruses

2018; Nature Portfolio; Volume: 3; Issue: 10 Linguagem: Inglês

10.1038/s41564-018-0227-2

2058-5276

Tracey Goldstein, Simon J. Anthony, Aiah A Gbakima, Brian H. Bird, James Bangura, Alexandre Tremeau‐Bravard, Manjunatha N. Belaganahalli, Heather Wells, Jasjeet Dhanota, Eliza Liang, Michael Grodus, Rohit K. Jangra, Veronica A. DeJesus, Gorka Lasso, Brett R. Smith, Amara Jambai, Brima Osaio Kamara, Sorie Mohamed Kamara, William Bangura, Corina Monagin, Sagi Shapira, Christine K. Johnson, Karen Saylors, Edward M. Rubin, Kartik Chandran, W. Ian Lipkin, Jonna A. K. Mazet,

Viral gastroenteritis research and epidemiology

Here we describe the complete genome of a new ebolavirus, Bombali virus (BOMV) detected in free-tailed bats in Sierra Leone (little free-tailed (Chaerephon pumilus) and Angolan free-tailed (Mops condylurus)). The bats were found roosting inside houses, indicating the potential for human transmission. We show that the viral glycoprotein can mediate entry into human cells. However, further studies are required to investigate whether exposure has actually occurred or if BOMV is pathogenic in humans.