Artigo Acesso aberto Revisado por pares

TGF-β–mediated enhancement of T H 17 cell generation is inhibited by bone morphogenetic protein receptor 1α signaling

2018; American Association for the Advancement of Science; Volume: 11; Issue: 545 Linguagem: Inglês

10.1126/scisignal.aar2125

ISSN

1937-9145

Autores

Lauren M. Browning, Maciej Pietrzak, Michal Kuczma, Colin Simms, Agnieszka Kurczewska, Justin Refugia, Dustin J. Lowery, Grzegorz A. Rempała, Dmitriy W. Gutkin, Leszek Ignatowicz, Pawel Muranski, Piotr Kraj,

Tópico(s)

Cytokine Signaling Pathways and Interactions

Resumo

BMP receptor 1α activation limits the TGF-β–mediated differentiation of CD4 + T cells that produce the cytokine IL-17.

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