TGF-β–mediated enhancement of T H 17 cell generation is inhibited by bone morphogenetic protein receptor 1α signaling
2018; American Association for the Advancement of Science; Volume: 11; Issue: 545 Linguagem: Inglês
10.1126/scisignal.aar2125
ISSN1937-9145
AutoresLauren M. Browning, Maciej Pietrzak, Michal Kuczma, Colin Simms, Agnieszka Kurczewska, Justin Refugia, Dustin J. Lowery, Grzegorz A. Rempała, Dmitriy W. Gutkin, Leszek Ignatowicz, Pawel Muranski, Piotr Kraj,
Tópico(s)Cytokine Signaling Pathways and Interactions
ResumoBMP receptor 1α activation limits the TGF-β–mediated differentiation of CD4 + T cells that produce the cytokine IL-17.
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