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Artigo Acesso aberto Produção Nacional Revisado por pares
BIBTEX RIS

Quality of life and associated factors in patients with chronic Chagas disease

2018; Wiley; Volume: 23; Issue: 11 Linguagem: Inglês

10.1111/tmi.13144

ISSN

1365-3156

Autores

João C. L. Santos‐Filho, Marcelo Carvalho Vieira, Isis Gabrielli Gomes Xavier, Erica Rodrigues Maciel, Luiz Fernando Rodrigues, Eduardo OV Curvo, Iane M. Pereira, Marcel de Souza Borges Quintana, Gilberto M. Sperandio da Silva, Henrique Horta Veloso, Fernanda S. N. S. Mendes, Alejandro Marcel Hasslocher‐Moreno, Andréa Silvestre de Sousa, Pedro Emmanuel Alvarenga Americano do Brasil, Roberto Magalhães Saraiva, Mauro Felippe Felix Mediano,

Tópico(s)

Trypanosoma species research and implications

Resumo

To evaluate the quality of life (QoL) of patients with Chagas disease (CD) and the association between QoL domains and several clinical, socioeconomic and lifestyle characteristics of this population.Cross-sectional observational study conducted from March 2014 to March 2017 including a total of 361 outpatients followed at Evandro Chagas National Institute of Infectious Disease, Brazil. QoL was assessed using the Portuguese shorter version of the original WHO Quality of Life questionnaire (WHOQOL-BREF). Information about clinical CD presentation, presence of comorbidities, functional class, previous benznidazole treatment, socioeconomic profile and lifestyle was also obtained.Environment and physical domains presented the worst QoL scores, while the social relationship domain presented the highest score. Multivariate regression analysis demonstrated that variables independently associated with QoL were functional class, sex, clinical presentation of CD, sleep duration, schooling, physical activity level, smoking, income per capita and residents by domicile.The low socioeconomic status and the physical limitations imposed by the disease presented an important impact on the QoL reduction among CD patients, especially on environment and physical domains. Strategies to improve QoL among CD patients should be tailored and consider many different variables to maximise improvements not only of patients' physical but also of their mental health.

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