In vitro degradation behavior of Mg scaffolds with three-dimensional interconnected porous structures for bone tissue engineering
2018; Elsevier BV; Volume: 144; Linguagem: Inglês
10.1016/j.corsci.2018.09.001
ISSN1879-0496
AutoresGaozhi Jia, Chenxin Chen, Jian Zhang, Yinchuan Wang, Rui Yue, Bérengère J.C. Luthringer - Feyerabend, Regine Willumeit–Römer, Hua Zhang, Meiping Xiong, Hua Huang, Guangyin Yuan, Frank Feyerabend,
Tópico(s)Orthopaedic implants and arthroplasty
ResumoThe degradation behavior in consideration of the pore strut and the interconnectivity of two Mg scaffolds with different three-dimensional interconnected porous structures were evaluated. The interconnectivity of the two scaffolds gradually decreased along with the clogged interconnected pores due to the deposition formation on the pore wall. Mg scaffold with spherical pores and cambered pore strut degraded faster but exhibited better resistance to the deterioration of the interconnectivity compared with Mg scaffold with irregular pores and polygonal pore struts. Direct cell culture of MC3T3-E1 osteoblasts on the two scaffolds indicated a promising potential for bone tissue engineering.
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