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Immunogenomic analyses associate immunological alterations with mismatch repair defects in prostate cancer

2018; American Society for Clinical Investigation; Volume: 128; Issue: 10 Linguagem: Inglês

10.1172/jci121924

1558-8238

Daniel Nava Rodrigues, Pasquale Rescigno, David Liu, Wei Yuan, Suzanne Carreira, Maryou Lambros, George Seed, Joaquı́n Mateo, Ruth Riisnaes, Stephanie A. Mullane, Claire A. Margolis, Diana Miao, Susana Miranda, David Dolling, Matthew Clarke, Cláudia Bertan, Mateus Crespo, Gunther Boysen, Ana Ferreira, Adam Sharp, Ines Figueiredo, Daniel Keliher, Saud H. AlDubayan, Kelly P. Burke, Semini Sumanasuriya, Mariane Fontes, Diletta Bianchini, Zafeiris Zafeiriou, Larissa Sena Teixeira Mendes, Kent W. Mouw, Michael T. Schweizer, Colin C. Pritchard, Stephen J. Salipante, Mary‐Ellen Taplin, Himisha Beltran, Mark A. Rubin, Marcin Cieślik, Dan R. Robinson, E. Heath, Nikolaus Schultz, Joshua Armenia, Wassim Abida, Howard I. Scher, Christopher J. Lord, Alan D. D’Andrea, Charles L. Sawyers, Arul M. Chinnaiyan, Andrea Alimonti, Peter S. Nelson, Charles G. Drake, Eliezer M. Van Allen, Johann S. de Bono,

Cancer Genomics and Diagnostics

BACKGROUND. Understanding the integrated immunogenomic landscape of advanced prostate cancer (APC) could impact stratified treatment selection.