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Highly Destructive Oral Basaloid Squamous Cell Carcinoma: a Case Report

2018; Elsevier BV; Volume: 126; Issue: 3 Linguagem: Inglês

10.1016/j.oooo.2018.02.317

2212-4411

Patrícia Guerra Peixe Gonçalves, Larissa Santos Amaral Rolim, Rodrigo Porpino Mafra, Hellen Bandeira de Pontes Santos, Hugo José Correia Lopes, Bruno César de Vasconcelos Gurgel, Leão Pereira Pinto,

Head and Neck Cancer Studies

Basaloid squamous cell carcinoma (BSCC) is uncommon in the oral cavity, being most frequently found in the upper aerodigestive tract. Here, we describe the case of a 63-year-old man who sought treatment at a surgery service with extensive injury in the oral cavity, with spontaneous bleeding, limiting mouth opening, dysphagia, and dysphonia. Computed tomography analysis showed marked destruction of the right body and angle of the mandible. An incisional biopsy was performed for anatomopathological examination, which showed proliferation and invasion of squamous and basaloid neoplastic epithelial cells in the trabeculae, islands, and cords, presenting wide areas of comedonecrosis, besides intense cellular pleomorphism and atypical and explosive mitoses. Thus, the diagnosis of BSCC was rendered and the patient was referred for oncologic treatment. Pathologists should be familiar with the histopathological aspects and destructive behavior of BSCC in order to establish a correct diagnosis and provide the best treatment for the patient.