Artigo Revisado por pares

Dying Healthy: Public Health Priorities for Fixed Population Life Expectancies

2018; American College of Physicians; Volume: 169; Issue: 8 Linguagem: Inglês

10.7326/m18-1609

ISSN

1539-3704

Autores

George J. Annas, Sandro Galea,

Tópico(s)

Palliative Care and End-of-Life Issues

Resumo

Ideas and Opinions16 October 2018Dying Healthy: Public Health Priorities for Fixed Population Life ExpectanciesGeorge J. Annas, JD, MPH and Sandro Galea, MD, DrPHGeorge J. Annas, JD, MPHBoston University School of Public Health, Boston, Massachusetts (G.J.A., S.G.) and Sandro Galea, MD, DrPHBoston University School of Public Health, Boston, Massachusetts (G.J.A., S.G.)Author, Article, and Disclosure Informationhttps://doi.org/10.7326/M18-1609 SectionsAboutFull TextPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail A longer life has long been one of the central goals of investments in public health and medicine. Population longevity is frequently used to measure the success of a country's health care system, and life expectancy in many countries increased by more than 30 years in the past century. The 21st century began with new medications and procedures to fight disease, and we are now at the dawn of a genomic revolution that has promised even more remarkable opportunities to cure disease and extend life. However, recent data suggest that the human lifespan probably has an unalterable biological limit of ...References1. Dong X, Milholland B, Vijg J. Evidence for a limit to human lifespan. Nature. 2016;538:257-9. [PMID: 27706136] doi:10.1038/nature19793 CrossrefMedlineGoogle Scholar2. Fries JF. Aging, natural death, and the compression of morbidity. N Engl J Med. 1980;303:130-5. [PMID: 7383070] CrossrefMedlineGoogle Scholar3. Frieden TR. Shattuck Lecture: the future of public health. N Engl J Med. 2015;373:1748-54. [PMID: 26510022] doi:10.1056/NEJMsa1511248 CrossrefMedlineGoogle Scholar4. Xu J, Murphy SL, Kochanek KD, Arias E. Mortality in the United States, 2015. NCHS Data Brief. 2016:1-8. [PMID: 27930283] MedlineGoogle Scholar5. Kontis V, Bennett JE, Mathers CD, Li G, Foreman K, Ezzati M. Future life expectancy in 35 industrialised countries: projections with a Bayesian model ensemble. Lancet. 2017;389:1323-35. [PMID: 28236464] doi:10.1016/S0140-6736(16)32381-9 CrossrefMedlineGoogle Scholar6. Fojo T, Mailankody S, Lo A. Unintended consequences of expensive cancer therapeutics—the pursuit of marginal indications and a me-too mentality that stifles innovation and creativity: the John Conley Lecture. JAMA Otolaryngol Head Neck Surg. 2014;140:1225-36. [PMID: 25068501] doi:10.1001/jamaoto.2014.1570 CrossrefMedlineGoogle Scholar7. Tannock IF, Hickman JA. Limits to personalized cancer medicine. N Engl J Med. 2016;375:1289-94. [PMID: 27682039] doi:10.1056/NEJMsb1607705 CrossrefMedlineGoogle Scholar8. Rao JK, Anderson LA, Smith SM. End of life is a public health issue. Am J Prev Med. 2002;23:215-20. [PMID: 12350455] CrossrefMedlineGoogle Scholar9. Callahan D. Death and the research imperative. N Engl J Med. 2000;342:654-6. [PMID: 10699168] CrossrefMedlineGoogle Scholar10. Fuchs VR. New priorities for future biomedical innovations. N Engl J Med. 2010;363:704-6. [PMID: 20818873] doi:10.1056/NEJMp0906597 CrossrefMedlineGoogle Scholar Author, Article, and Disclosure InformationAffiliations: Boston University School of Public Health, Boston, Massachusetts (G.J.A., S.G.)Disclosures: Authors have disclosed no conflicts of interest. Forms can be viewed at www.acponline.org/authors/icmje/ConflictOfInterestForms.do?msNum=M18-1609.Corresponding Author: Sandro Galea, MD, DrPH, Office of the Dean, 715 Albany Street, Talbot 301, Boston University School of Public Health, Boston, MA 02118; e-mail, [email protected]edu.Current Author Addresses: Dr. Annas: Center for Health Law, Ethics & Human Rights, 715 Albany Street, Talbot, Boston University School of Public Health, Boston, MA 02118.Dr. Galea: Office of the Dean, 715 Albany Street, Talbot 301, Boston University School of Public Health, Boston, MA 02118.Author Contributions: Conception and design: S. Galea.Drafting of the article: G.J. Annas, S. Galea.Critical revision of the article for important intellectual content: G.J. Annas, S. Galea.Final approval of the article: G.J. Annas, S. Galea.Administrative, technical, or logistic support: S. Galea.This article was published at Annals.org on 25 September 2018. 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Cunningham, PhD, and James Curran, MD 16 October 2018Volume 169, Issue 8Page: 568-569KeywordsCancer preventionHealth economicsLife expectancyPalliative carePatientsPrecision medicinePrevention, policy, and public healthQuality of lifeResearch fundingSafety ePublished: 25 September 2018 Issue Published: 16 October 2018 Copyright & PermissionsCopyright © 2018 by American College of Physicians. All Rights Reserved.PDF downloadLoading ...

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