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Clinical and Morphological Features of Sialadenoma Papilliferum: Report of Three Cases

2018; Elsevier BV; Volume: 126; Issue: 3 Linguagem: Inglês

10.1016/j.oooo.2018.02.316

2212-4411

Patrícia Guerra Peixe Gonçalves, Hellen Bandeira de Pontes Santos, Caio César da Silva Barros, Márcia Cristina da Costa Miguel, Lélia Batista de Souza, Hébel Cavalcanti Galvão, Roseana de Almeida Freitas,

Ear and Head Tumors

Sialadenoma papilliferum (SP), a rare and benign neoplasm of the salivary gland, accounts for approximately 1% of the minor salivary gland tumors. Here, we report 3 cases of SP, addressing their clinical and histopathological aspects. Each case presented as an exophytic and asymptomatic nodule in the palate. Under the hypothesis of squamous papilloma (case 1), fibrous hyperplasia (case 2), and sialadenitis (case 3), an excisional biopsy was performed. Microscopically, all the cases presented similar aspects, multiple exophytic papillary projections covered by stratified squamous epithelium that was contiguous with a proliferation of papillomatous ductal epithelium found below the surface. The basal cuboidal cell layer and a columnar cell luminal layer mostly lined the cystically dilated ducts and papillary projections. The supporting connective tissue contained a moderate mononuclear inflammatory infiltrate. Based on these findings, the 3 cases were diagnosed as SP, and there has been no evidence of recurrence after 5 years.