Artigo Acesso aberto Revisado por pares

ORAL AB AGORA1362Cardiac Involvement in Patients With Different Rheumatic Disorders1366Gender differences in the development of cardiac complications: a multicentric prospective study in a large cohort of thalassemia major patients1646Comparison of T1-mapping, T2-weighted and contrast-enhanced cine imaging at 3.0T CMR for diagnostic oedema assessment in ST-segment elevation myocardial infarction1375Evaluation of Tissue Changes in Remote Noninfarcted Myocardium after Acute Myocardial Infarction …

2016; Oxford University Press; Volume: 17; Issue: suppl 1 Linguagem: Inglês

10.1093/ehjci/jew181

ISSN

2047-2412

Autores

Simon Greulich, Antonella Meloni, Sheraz A. Nazir, P. Stefan Biesbroek, Nisha Arenja, Andreas A. Kammerlander, Aatif Sayeed, F. Ricci, Peter Bernhardt, Christian Meierhofer, Daniel G. H. Devos, Beate Ruecker, Barbara Burkhardt, Vivian P. Kamphuis, Manuel De Lazzari, Ineke Nederend, Lydia Dux‐Santoy, João L. Cavalcante, Stefania Rosmini, Bin Liu, Graham Fent, Guido Claessen, Jonathan M. Behar, S. Oebel, A. Baritussio, Jayanth R. Arnold, Daniel Kitterer, Joerg Latus, Jessica Kristin Henes, Rebekka Kurmann, Steffen Gloekler, Andreas Wahl, Sebastian J. Buss, Hugo A. Katus, Marco Bobbo, M. Lombardi, N. Braun, Mark Dominik Alscher, Udo Sechtem, Heiko Mahrholdt, Marcella Neri, P Preziosi, Emanuele Grassedonio, Nicolò Schicchi, P. Keilberg, Stefano Pulini, Elena Facchini, Vincenzo Positano, A. Pepe, Abhishek Shetye, Jamal Nasir Khan, Anvesha Singh, Prathap Kanagala, Daniel Swarbrick, Gaurav S. Gulsin, Matthew Graham‐Brown, Iain Squire, Anthony Gershlick, Gerry P McCann, Raquel P. Amier, Paul F. Teunissen, Lourens Robbers, Aernout M. Beek, Albert C. van Rossum, Mark B.M. Hofman, Niels van Royen, Robin Nijveldt, Johannes Riffel, Charly Noel Djiokou, Florian André, Thomas Fritz, Manuel Halder, Z. Thomas, Grigorios Korosoglou, Hugo A. Katus, Sebastian J. Buss, Marianne L. Schwaiger, Franz Duca, Stefan Aschauer, Beatrice A. Marzluf, Caroline Zotter‐Tufaro, Daniel Dalos, Stefan Pfaffenberger, Diana Bonderman, Julia Mascherbauer, Yaron Fridman, Brianne Hackman, Ajay Kadakkal, Maren Maanja, Hussein Abu Daya, Timothy C. Wong, Erik B. Schelbert, Andrea Barison, Giancarlo Todiere, R. Gaeta, S. Galllina, Michele Emdin, R De Caterina, G.D. Aquaro, Dominik Buckert, Nils Dyckmanns, Wolfgang Rottbauer, Andreas Kühn, Nerejda Shehu, Jan Müller, Heiko Stern, Peter Ewert, Sohrab Fratz, Manfred Vogt, Katya De Groote, Danilo Babin, Laurent Demulier, Yves Taeymans, Jos Westenberg, Luc Van Bortel, Patrick Segers, Eric Achten, Jean De Schepper, Ernst Rietzschel, Julia Geiger, Malek Makki, Barbara Burkhardt, Christian J. Kellenberger, Emanuela R. Valsangiacomo Buechel, Christian J. Kellenberger, Julia Geiger, B. Ruecker, Emanuela R. Valsangiacomo Buechel, Mohammed S.M. Elbaz, Lucia J.M. Kroft, Rob J. van der Geest, Albert de Roos, Nico A. Blom, Jos J.M. Westenberg, Arno A.W. Roest, Alberto Cipriani, Angela Susana, Stefania Rizzo, Benedetta Giorgi, Lacognata Carmelo, Emanuele Bertaglia, Barbara Bauce, Domenico Corrado, Gaetano Thiene, Martina Perazzolo Marra, Cristina Basso, Sabino Iliceto, Arno A.W. Roest, Peter J. Boogaard, Arend D.J. ten Harkel, Eco J. C. de Geus, Lucia J.M. Kroft, Albert de Roos, J.J.M. Westenberg, Raquel Kale, Gisela Teixidó‐Turà, Giuliana Maldonado, Marina Huguet, David García‐Dorado, Artur Evangelista, José F. Rodríguez‐Palomares, Shasank Rijal, John Schindler, Thomas G. Gleason, Joon S. Lee, Erik B. Schelbert, Heerajnarain Bulluck, Thomas A. Treibel, Anish Bhuva, Amna Abdel‐Gadir, Verónica Culotta, Ahmed Merghani, Viviana Maestrini, Anna S Herrey, Peter Kellman, Charlotte Manisty, James Moon, Manvir Hayer, S. Baig, Tejas Shah, S Rooney, Nicola C. Edwards, Richard P. Steeds, Pankaj Garg, Peter Swoboda, Laura E Dobson, T.A. Musa, John Foley, P. Haaf, John P. Greenwood, Sven Plein, Frank T. Schnell, J. Bogaert, Steven Dymarkowski, Nele Pattyn, P. Claus, Jolien Van Cleemput, A. La Gerche, Hein Heidbüchel, Daniel Toth, Sabrina Reiml, Maria Panayiotou, Simon Claridge, Tom Jackson, Manav Sohal, Jessica Webb, Mark O’Neill, Alexander Brost, Peter Mountney, Reza Razavi, Kawal Rhode, Christopher A. Rinaldi, A. Arya, S. Hilbert, A. Bollmann, G. Hindricks, Cosima Jahnke, I. Paetsch, B. Dinov, M. Perazzolo Marra, Aniruddha Dastidar, J. Rodrigues, Alessandro Zorzi, Angela Susana, Alessandra Scatteia, E. De Garate, Giulia Mattesi, Julian Strange, Domenico Corrado, Chiara Bucciarelli‐Ducci, Michael Jerosch‐Herold, Theodoros D. Karamitsos, Jane M Francis, Paul Bhamra‐Ariza, Rizwan Sarwar, Robin Choudhury, Joseph B. Selvanayagam, Stefan Neubauer,

Tópico(s)

Cardiovascular Function and Risk Factors

Resumo

Purpose: There is much controversy about the prevalence of cardiac involvement in patients with rheumatic disorders.This is of importance, since consequences of cardiac involvement range from different treatment regimes to adverse outcomes.Consequently, our primary aim was to evaluate the prevalence of cardiac involvement in different forms of rheumatic disorders by CMR.Methods: 297 patients underwent CMR.Cardiac involvement was defined by presence of late gadolinium enhancement (LGE).Patients with a history of myocardial infarction and/ or prior revascularization procedure were excluded.Patients were further divided into 5 subgroups: (1) ANCA associated vasculitis, (2) non-ANCA associated vasculitis, (3) autoimmune connective tissue disorders, (4) arthritis, and (5) sarcoidosis.Results: We enrolled n ¼ 63 patients in the ANCA associated vasculitis group, 34 of them (54%) were LGE positive.LGE showed a non-ischemic pattern in 33 patients (97%), isolated ischemic LGE pattern was present in only 1 patient.The Non-ANCA associated vasculitis group consisted of 32 patients, in 7 patients (22%) LGE could be detected.LGE was non-ischemic in 6 patients (86%), isolated ischemic LGE was present in only 1 patient.In the group with connective tissue disorders 15 out of 110 patients (14%) showed LGE: Of these, 13 patients (87%) showed non-ischemic LGE, 2 patients isolated ischemic LGE, 2 patients had both non-ischemic and ischemic pattern.The Arthritis group consisted of 47 patients, in 10 of them (21%) LGE was detected.Non-ischemic LGE pattern was found in 8 patients (80%), ischemic LGE was present in 3 patients (30%), in one patient LGE-CMR revealed both LGE patterns.45 patients were in the sarcoid group, 11 of them (24%) showed LGE: 8 patients had non-ischemic LGE (73%), 3 patients ischemic LGE (27%).Comparing prevalence of cardiac involvement in the five different rheumatic subgroups, the highest prevalence of cardiac involvement (54%) was detected in patients with ANCA-associated vasculitis.Conversely, in our cohort of autoimmune connective tissue disorders, LGE CMR revealed the lowest prevalence of cardiac involvement.Conclusion: There is a wide variation in the prevalence of cardiac involvement in different groups with rheumatic disorders.In patients with ANCA associated vasculitis cardiac involvement seems to be common (54%), whereas patients with autoimmune connective tissue disorders seem to have a low prevalence of cardiac involvement (14%).

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