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C-Reactive protein as a diagnostic tool in differential diagnosis of hypereosinophilic syndrome and antineutrophil cytoplasmic antibody–negative eosinophilic granulomatosis with polyangiitis

2018; Elsevier BV; Volume: 7; Issue: 4 Linguagem: Inglês

10.1016/j.jaip.2018.10.002

2213-2201

Amélie Leurs, Cécile Chenivesse, Benjamín López, Jean‐Baptiste Gibier, Guillaume Clément, Matthieu Groh, Marie‐Christine Copin, D. Staumont‐Sallé, G. Mortuaire, Marie-Hélène Balquet, F. Dezoteux, Nathalie Bautin, Anne-Laure Buchdahl, N. Le Gouellec, Nicolas Etienne, Louis Terriou, Sylvain Dubucquoi, Myriam Labalette, S. Morell‐Dubois, H. Maillard-Lefebvre, M. Lambert, É. Hachulla, David Launay, Jean‐Emmanuel Kahn, Pierre‐Yves Hatron, Guillaume Lefèvre,

Urticaria and Related Conditions

The differential diagnosis of hypereosinophilic syndrome (HES) and eosinophilic granulomatosis with polyangiitis (EGPA) can be challenging in the context of asthma, blood eosinophilia, and systemic manifestations. EGPA (Churg-Strauss syndrome) differs from other antineutrophil cytoplasmic antibody (ANCA)-associated vasculitides by the constant presence of asthma, blood eosinophilia, and presence of ANCAs (usually with myeloperoxidase [MPO] specificity, MPO/ANCAs) in only 30% or so of cases.1-3