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Perinatal Outcomes in Vertically Infected Neonates During a Chikungunya Outbreak on the Island of Curaçao

2018; American Society of Tropical Medicine and Hygiene; Volume: 99; Issue: 6 Linguagem: Inglês

10.4269/ajtmh.17-0957

1476-1645

Bert J. D. van Enter, Minke H. W. Huibers, Linda van Rooij, Radjinkoemar Steingrover, Michaël Boele van Hensbroek, Ralph R. Voigt, Jeroen Hol,

Viral Infections and Outbreaks Research

Recent outbreaks of Chikungunya virus (CHIKV) infection confirm the vulnerability of neonates after vertical transmission. In 2014, CHIKV was reported for the first time in the Americas, including the island of Curaçao. We describe the outcomes of symptomatic neonates with vertically transmitted CHIKV infection during the CHIKV epidemic, who were admitted in the Saint Elisabeth Hospital, Willemstad, Curaçao. There were three symptomatic neonates with serologically confirmed infection. Two neonates developed neurological complications, including convulsions and intracerebral bleeding. One newborn, in whom maternal infection occurred 7 weeks before delivery, had a fatal outcome after birth. Maternal-fetal transmission of CHIKV may cause severe neonatal complications. There is a need to share experiences and to implement protocols toward the management of perinatal CHIKV infection.