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Influence of potassium levels on one-year outcomes in elderly patients with acute heart failure

2018; Elsevier BV; Volume: 60; Linguagem: Inglês

10.1016/j.ejim.2018.10.016

1879-0828

Françesc Formiga, David Chivite, Xavier Corbella, Alicia Conde‐Martel, José Carlos Arévalo‐Lorido, Joan Carles Trullàs, J. Pérez-Silvestre, Sara Carrascosa García, Luís Manzano, Manuel Montero-Pérez-Barquero,

Membrane-based Ion Separation Techniques

Background Abnormal serum potassium levels (K+) in patients with heart failure (HF) relate to worse prognosis. We evaluated whether admission K+ levels predict 1-year outcomes in elderly patients admitted for acute HF. Methods We evaluated 2865 patients aged >74 years from the RICA Spanish Heart Failure Registry, classified according to admission serum K+ levels: hyperkalemia (>5.5 mmol/L), normokalemia (3.5–5.5 mmol/L) and hypokalemia ( 5.5 mmol/L and 1.08 (p = .618) and 0.90 (p = .533) respectively for K+ < 3.5 mmol/L. The HR for the combined outcome was 1.59 (1.19–2.13); p = .002 in hyperkalemic patients and 0.96 (0.75–1.23); p = .751in hypokalemic patients. Multivariate analysis showed a significant association of admission K+ values >5.5 mmol/L with the combined outcome of mortality and readmission (HR 1.15 [95% CI 1.04–1.27], p = .008). Conclusion In patients hospitalized for decompensated HF, admission hyperkalemia predicts a higher mid-term risk for HF readmission and mortality, probably related to the significant higher risk of readmission.