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Risks associated with fat burners: A toxicological perspective

2018; Elsevier BV; Volume: 123; Linguagem: Inglês

10.1016/j.fct.2018.10.051

1873-6351

Žiga Jakopin,

Phytochemicals and Antioxidant Activities

Dietary supplements “fat burners”, freely available on the market, are intended to promote weight loss and reduce fat accumulation, either via stimulation of lipolysis or by inhibition of lipogenesis. Proponents claim that fat burners can increase fat metabolism, although their usefulness remains controversial. Fat burners are usually claimed to be of natural origin and viewed as being inherently safe. This review focuses on the most common ingredients of natural origin usually found in the fat burners, their molecular mechanisms of action and the toxicological profiles of these compounds in order to gain an insight into their safety.