A8447 Total body water content in South East Asian hypertensive patients
2018; Lippincott Williams & Wilkins; Volume: 36; Linguagem: Inglês
10.1097/01.hjh.0000548082.79380.d8
ISSN1473-5598
Autores Tópico(s)Nutrition and Health in Aging
ResumoObjectives: To date, several guidelines suggest diuretics as a possible first line treatment choice in elderly patients with isolated systolic hypertension. In any individual patient, hypertension is due to increased vascular resistance, blood volume or cardiac output, or a mixed effect thereof. These physiological parameters can be assessed through cardiac bioimpedance. The objective of this study was to establish whether excess Total Body Water (TBW) indeed is a major contributor to hypertension in the elderly. Methods: We assessed TBW via cardiac bioimpedance in 70 patients with hypertension using the NI Medical NICAS device. Patients were grouped into the category “old” if over 60 years, and “young” if below age 60. Total body water content as measured using the device was correlated with age, as well as BMI. Results: 19 older patients, average age 71.3 + 9.8 years, were compared to 51 younger patients with average age 36.7 + 11.4 years. Figure 1 shows TBW measurements correlated to age and body mass index (BMI). TBW significantly correlated with BMI, but not with age (p = 0.324). TBW was 47.4 + 8.4% in young, and 45.3 + 6.9% in old patients. Conclusion: The reference range for TBW is 45.8–60.3%. As such, our population's hydration status was at the lower end of the normal range. Values were in the same range as those reported for healthy young Indonesians (Guricci 1999), but considerably lower than those in Northern Chinese (Jiang 1991) or Indians (Borgonha 1996). The overall relatively low TBW of hypertensive Singaporeans, without age related increase, calls to question the advice to use diuretics as a first line antihypertensive treatment in isolated systolic hypertension in the elderly.
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