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BIBTEX RIS

Immunogenicity of Clostridium perfringens epsilon toxin recombinant bacterin in rabbit and ruminants

2018; Elsevier BV; Volume: 36; Issue: 50 Linguagem: Inglês

10.1016/j.vaccine.2018.10.081

1873-2518

Marcos Roberto Alves Ferreira, Francisco D. dos Santos, Carlos Eduardo Pouey da Cunha, Clóvis Moreira, Rafael Amaral Donassolo, Carolina Georg Magalhães, Alessandra S. Belo Reis, Carlos Magno Chaves Oliveira, José Diomedes Barbosa, Fábio Pereira Leivas Leite, Felipe Masiero Salvarani, Fabrício Rochedo Conceição,

Botulinum Toxin and Related Neurological Disorders

• Inactivated recombinant E. coli expressing rETX (recombinant bacterin). • Non-purified vaccine induced protective immunity in rabbits, sheep and cattle. • Recombinant vaccines are produced using a safe, simpler and faster production process. • Production process requires no steps of lysis, purification and refolding.