Produção Nacional
Revisado por pares
Human In Situ Study of the effect of Bis(2-Methacryloyloxyethyl) Dimethylammonium Bromide Immobilized in Dental Composite on Controlling Mature Cariogenic Biofilm
2018; Multidisciplinary Digital Publishing Institute; Volume: 19; Issue: 11 Linguagem: Inglês
10.3390/ijms19113443
ISSN1661-6596
AutoresMary Anne S. Melo, Michael D. Weir, Vanara Florêncio Passos, Juliana Paiva Marques Lima Rolim, Christopher D. Lynch, Lidiany Karla Azevedo Rodrigues, Hockin H.K. Xu,
Tópico(s)Dental Erosion and Treatment
ResumoCariogenic oral biofilms cause recurrent dental caries around composite restorations, resulting in unprosperous oral health and expensive restorative treatment. Quaternary ammonium monomers that can be copolymerized with dental resin systems have been explored for the modulation of dental plaque biofilm growth over dental composite surfaces. Here, for the first time, we investigated the effect of bis(2-methacryloyloxyethyl) dimethylammonium bromide (QADM) on human overlying mature oral biofilms grown intra-orally in human participants for 7⁻14 days. Seventeen volunteers wore palatal devices containing composite specimens containing 10% by mass of QADM or a control composite without QADM. After 7 and 14 days, the adherent biofilms were collected to determine bacterial counts via colony-forming unit (CFU) counts. Biofilm viability, chronological changes, and percentage coverage were also determined through live/dead staining. QADM composites caused a significant inhibition of
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