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Hepatitis C virus genotypes in hemodialysis patients in Angola

2018; Wiley; Volume: 91; Issue: 3 Linguagem: Inglês

10.1002/jmv.25354

1096-9071

Luis Filipe da Costa Marques Borges, Mariano Zalis, Guilherme Santoro‐Lopes, Rafael Brandão Varella,

Liver Disease Diagnosis and Treatment

To our knowledge, there are no published data on hepatitis C virus (HCV) genotypes in Angola. This study aimed at assessing the distribution of HCV genotypes in seropositive hemodialysis patients in Luanda. Among 51 HCV‐positive subjects included, viremia was detected in 27 (53%). HCV genotyping was performed by bidirectional sequencing of the 5'‐untranslated region by the Sanger method. HCV genotype 4 was largely predominant (20 cases; 74%), followed by genotypes 1b (5 cases; 18.5%), 1a and 2 (one case each; 3.7%). These results suggest that the distribution of HCV genotypes in Angola is similar to that reported from other Central African countries.