Produção Nacional
The Interactions Between Obesity, Sleep Quality, and Chronic Pain
2018; American Academy of Sleep Medicine; Volume: 14; Issue: 11 Linguagem: Inglês
10.5664/jcsm.7510
ISSN1550-9397
AutoresPriscila K. Morelhão, Sérgio Tufik, Mônica L. Andersen,
Tópico(s)Sleep and Work-Related Fatigue
ResumoFree AccessSleep QualityThe Interactions Between Obesity, Sleep Quality, and Chronic Pain Priscila K. Morelhão, MSc, Sergio Tufik, PhD, Monica L. Andersen, PhD Priscila K. Morelhão, MSc Department of Physical Therapy, Faculty of Science and Technology, Sao Paulo State University (UNESP), Presidente Prudente, São Paulo, Brazil , Sergio Tufik, PhD Departamento de Psicobiologia, Universidade Federal de São Paulo, São Paulo, Brazil , Monica L. Andersen, PhD Address correspondence to: Monica Levy Andersen, PhD, Universidade Federal de São Paulo, Napoleão de Barros, 925, Vila Clementino - 04024-002, São Paulo/SP – Brazil+55 11 2149-0155+55 11 55725092 E-mail Address: [email protected] Departamento de Psicobiologia, Universidade Federal de São Paulo, São Paulo, Brazil Published Online:November 15, 2018https://doi.org/10.5664/jcsm.7510Cited by:2SectionsPDF ShareShare onFacebookTwitterLinkedInRedditEmail ToolsAdd to favoritesDownload CitationsTrack Citations AboutINTRODUCTIONObesity has become a major global public health problem and is associated with a range of comorbidities including sleep disturbance and chronic pain.1 There have been numerous studies on the associations between obesity, sleep, and pain, and on how and in which direction they influence each other.1,2 Sleep debt, chronic pain, weight gain, and significant hormonal changes have all been suggested as possible outcomes of these relationships.3–5 Results from a meta-analysis have shown that twins who are overweight are twice as likely to have low back pain compared to those of normal weight or below weight.6 An example of this complex interaction can be found in some individuals with chronic pain, who may be restricted in their movement and become less active, thereby contributing to weight gain which, in turn, has been shown to be associated with sleep restriction.The literature shows that obesity can contribute to chronic pain through two main mechanisms: mechanical stress, with excess body weight causing stress on joints in the musculo-skeletal system; and systemic proinflammatory status, which is associated with obesity and can worsen pain.7 Conversely, chronic pain can contribute to obesity through limiting physical activity because of fear of movement.7 Other studies have shown body mass index (BMI) to be associated with pain, disability, depression, anxiety, reduced physical function,8 and lack of sleep.9Several studies have demonstrated that sleep deprivation is associated with obesity in adults3,10 through modifying appetite-regulating hormones and increasing caloric intake. The mechanism can be explained by sleep deprivation causing an imbalance between leptin and ghrelin. Leptin and ghrelin are peripheral signals that interact with the hypothalamic arcuate nucleus and modulate orexin system activity to decrease or increase food intake.10 When there is sleep restriction, ghrelin increases whereas leptin decreases, therefore contributing to increased food intake. Previous studies have demonstrated that short sleep was also associated with unbalanced leptin and ghrelin and that these hormonal changes can result in increased BMI, which in turn can have negative effects on sleep.3Therefore, we would like to highlight the mechanisms involved in obesity and the important relationship between obesity, sleep, and chronic pain. Modern lifestyles have tended to produce more sedentary populations who consume more food and sleep less,11 which has contributed to an increase in chronic diseases and less healthy populations. Thus, it is essential to implement awareness and prevention strategies that consider the relationships between all these factors in order to combat the risks to health. Changing behaviors is not easy, but it needs to be done given their current effect on health.DISCLOSURE STATEMENTThe authors are supported by grants from the Associacao Fundo de Incentivo à Pesquisa (AFIP) and the Sao Paulo Research Foundation. MLA and ST are CNPq fellowship recipients. PKM is supported by a grant from the Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES). The authors report no conflicts of interest.CITATIONMorelhão PK, Tufik S, Andersen ML. The interactions between obesity, sleep quality, and chronic pain. J Clin Sleep Med. 2018;14(11):1965–1966.REFERENCES1 Arranz LI, Rafecas M, Alegre CEffects of obesity on function and quality of life in chronic pain conditions. Curr Rheumatol Rep; 2014;161:390, 24264719. 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CrossrefGoogle Scholar Previous article FiguresReferencesRelatedDetailsCited by The Relationship Between Experiences of Pain Among Youth with Obesity and Health-Related Quality of Life: The Role of Functional Limitation, Sleep, and Depressive SymptomsTheriault C, DiPlacido J, Zempsky W and Santos M Childhood Obesity, 10.1089/chi.2022.0203 Diet/Nutrition: Ready to Transition from a Cancer Recurrence/Prevention Strategy to a Chronic Pain Management Modality for Cancer Survivors?Tümkaya Yılmaz S, Malfliet A, Elma Ö, Deliens T, Nijs J, Clarys P, De Groef A and Coppieters I Journal of Clinical Medicine, 10.3390/jcm11030653, Vol. 11, No. 3, (653) Volume 14 • Issue 11 • November 15, 2018ISSN (print): 1550-9389ISSN (online): 1550-9397Frequency: Monthly Metrics History Submitted for publicationAugust 20, 2018Submitted in final revised formAugust 20, 2018Accepted for publicationSeptember 6, 2018Published onlineNovember 15, 2018 Information© 2018 American Academy of Sleep MedicinePDF download
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